Meclixine Tablet
Meclizine Hydrochloride + Pyridoxine Hydrochloride
General Pharmaceuticals Ltd.
| Pack size | 50's pack |
|---|---|
| Unite Price | 3.00 BDT |
Indications
Meclixine Tablet is used for:
Nausea, vomiting, dizziness, motion sickness, radiation sickness and vertigo associated with diseases of vestibular motion sickness, radiation sickness and vertigo associated with diseases of vestibular system, morning sickness during pregnancy, drug induced nausea, vomiting induced by oral contraceptives or Estrogen preparations.
Adult Dose
Oral
Motion sickness
Adult: 25-50 mg Meclizine 1 hr before travelling and repeat 24 hrly if needed.
Vertigo and vestibular disorders
Adult: 25-100 mg Meclizine daily in divided doses. Discontinue if there is no response after 1-2 wk of treatment.
Radiation sickness:
50 mg Meclizine administered 2-12 hours prior to radiation treatment.
Pyridoxine (vitamin B6) has been shown to be safe and effective in dosages of 50 to 200 mg per day.
Child Dose
Oral
<12 years: Safety and efficacy not established
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Meclizine Hydrochloride and Pyridoxine Hydrochloride is contraindicated in patients who are hypersensitive to these ingredients.
Precautions
Prostate hypertrophy, obstruction of bladder neck, narrow angle glaucoma, pyloric stenosis. May impair ability to drive or operate machinery. Pregnancy.
Lactation: Not known if excreted in milk; use caution
Pregnancy-Lactation
Interactions
Additive effects with CNS depressants, neuroleptics, anticholinergics, alcohol.
Side Effects
Side effects of Meclizine Hydrochloride + Pyridoxine Hydrochloride :
Drowsiness, thickening of bronchial secretions, dry mouth, fatigue, blurred vision.
Mode of Action
Meclozine blocks vasopressor response to histamine and has a slight blocking action against acetylcholine. It decreases excitability of the middle ear labyrinth and blocks conduction in the middle ear vestibular-cerebellar pathways.
Pyridoxine is a water-soluble vitamin which functions in the metabolism of carbohydrates, proteins and fats. It is essential in Hb formation and GABA synthesis within the CNS. It also aids in the release of glycogen stored in the liver and muscles.
Note
Meclixine Tablet generic name is Meclizine Hydrochloride + Pyridoxine Hydrochloride. Meclixine Tablet is manufactured by General Pharmaceuticals Ltd.Meclixine is availble in all over Bangladesh.
Mes BD drug index information on Meclixine Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.