Maxbuten DS Syrup
Ceftibuten
180 mg/5 ml
Synovia Pharma PLC.
| Pack size | 60 ml bot |
|---|---|
| Unite Price | 800.00 BDT |
Indications
Maxbuten DS Syrup is used for:
Respiratory tract infections, Urinary tract infections
Adult Dose
Oral
Respiratory tract infections, Urinary tract infections
Adult: 400 mg once daily for 10 days.
Child Dose
Child:
<6 months: Safety and efficacy not established
6-12 years old or <45 kg: 9 mg/kg PO qDay; 400 mg/day PO for 10 days maximum
>12 years old or >45 kg: As in adults
Renal Dose
Renal impairment:
CrCl (ml/min)
30-49 200 mg once daily.
5-29 100 mg once daily.
Administration
Susp: Should be taken on an empty stomach. Take 2 hr before or 1 hr after meals.
Cap: May be taken with or without food.
Contra Indications
Hypersensitivity to cephalosporins.
Precautions
Hypersensitivity to penicillins; renal impairment; Porphyria. Monitor renal and haematologic status.
Lactation: excretion in milk unknown; use with caution
Pregnancy-Lactation
Pregnancy Category: B
Lactation: excretion in milk unknown; use with caution
Interactions
Enhanced nephrotoxicity of aminoglycosides. Increased serum concentration w/ probenecid. Decreased serum concentration w/ zinc salts.
Side Effects
Side effects of Ceftibuten :
1-10%
Increased BUN (4%), Nausea (4%), Diarrhea (3%), Headache (3%), Increased eosinophils (3%), Decreased hemoglobin (2%), Dyspepsia (2%), Thrombocytosis (2%), Abdominal pain (1%), Dizziness (1%), Increased ALT (1%), Increased bilirubin (1%), Vomiting (1%)
<1%
Anorexia, Candidiasis, Constipation, Dysuria, Agitation, Fatigue, Insomnia, Irritability, Paresthesia, Rigors, Diaper rash, Urticaria, Dry mouth, Dyspnea, Nasal congestion, Increased transaminases, Increased creatinine, Leukopenia
Potentially Fatal: Pseudomembranous colitis.
Mode of Action
Ceftibuten inhibits bacterial cell wall synthesis. It is stable to hydrolysis by many beta-lactamases and has greater activity than 1st or 2nd generation cephalosporins against gm-ve bacteria. It is less active in vitro than cefexime against S. pneumoniae.
Note
Maxbuten DS 180 mg/5 ml Syrup generic name is Ceftibuten. Maxbuten DS 180 mg/5 ml Syrup is manufactured by Synovia Pharma PLC.Maxbuten DS is availble in all over Bangladesh.
Mes BD drug index information on Maxbuten DS Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.