Maxbuten Syrup

Ceftibuten
90 mg/5 ml
Synovia Pharma PLC.
Pack size 60 ml bot
Unite Price 480.00 BDT

Indications

Maxbuten Syrup is used for: Respiratory tract infections, Urinary tract infections

Adult Dose

Oral Respiratory tract infections, Urinary tract infections Adult: 400 mg once daily for 10 days.

Child Dose

Child: <6 months: Safety and efficacy not established 6-12 years old or <45 kg: 9 mg/kg PO qDay; 400 mg/day PO for 10 days maximum >12 years old or >45 kg: As in adults

Renal Dose

Renal impairment: CrCl (ml/min) 30-49 200 mg once daily. 5-29 100 mg once daily.

Administration

Susp: Should be taken on an empty stomach. Take 2 hr before or 1 hr after meals. Cap: May be taken with or without food.

Contra Indications

Hypersensitivity to cephalosporins.

Precautions

Hypersensitivity to penicillins; renal impairment; Porphyria. Monitor renal and haematologic status. Lactation: excretion in milk unknown; use with caution

Pregnancy-Lactation

Pregnancy Category: B Lactation: excretion in milk unknown; use with caution

Interactions

Enhanced nephrotoxicity of aminoglycosides. Increased serum concentration w/ probenecid. Decreased serum concentration w/ zinc salts.

Side Effects

Side effects of Ceftibuten : 1-10% Increased BUN (4%), Nausea (4%), Diarrhea (3%), Headache (3%), Increased eosinophils (3%), Decreased hemoglobin (2%), Dyspepsia (2%), Thrombocytosis (2%), Abdominal pain (1%), Dizziness (1%), Increased ALT (1%), Increased bilirubin (1%), Vomiting (1%) <1% Anorexia, Candidiasis, Constipation, Dysuria, Agitation, Fatigue, Insomnia, Irritability, Paresthesia, Rigors, Diaper rash, Urticaria, Dry mouth, Dyspnea, Nasal congestion, Increased transaminases, Increased creatinine, Leukopenia Potentially Fatal: Pseudomembranous colitis.

Mode of Action

Ceftibuten inhibits bacterial cell wall synthesis. It is stable to hydrolysis by many beta-lactamases and has greater activity than 1st or 2nd generation cephalosporins against gm-ve bacteria. It is less active in vitro than cefexime against S. pneumoniae.

Note

Maxbuten 90 mg/5 ml Syrup generic name is Ceftibuten. Maxbuten 90 mg/5 ml Syrup is manufactured by Synovia Pharma PLC.Maxbuten is availble in all over Bangladesh. Mes BD drug index information on Maxbuten Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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