Ludiomil Tablet
Maprotiline Hydrochloride
25mg
Novartis (Bangladesh) Ltd.
| Pack size | 5's pack |
|---|---|
| Unite Price | 6.50 BDT |
Indications
Ludiomil Tablet is used for:
Depression
Adult Dose
Oral
Depression
Adult: As hydrochloride: 25-75 mg daily in 3 divided doses, gradually increased in 25 mg increments at 1-2 wk intervals to 150 mg/day if necessary. Up to 225 mg/day in severely depressed patients.
Elderly: Initial: 25 mg daily. May increase slowly according to response to 50-75 mg daily if needed.
Child Dose
Safety and effecay not established
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Preexisting CV insufficiency; epilepsy or lowered seizure threshold.
Precautions
Urinary retention, prostatic hyperplasia, chronic constipation, untreated angle-closure glaucoma; hyperthyroidism; risk of suicide; may precipitate mania or psychotic symptoms; withdraw gradually; may impair ability to operate machinery. Pregnancy and lactation; elderly.
Lactation: avoid during breastfeeding
Pregnancy-Lactation
Pregnancy Category: B
Lactation: avoid during breastfeeding
Interactions
MAOIs. Increase in sedative effect with alcohol. Increased effect of antidiabetics. Maprotiline concentrations and toxicity increased by propranolol, risperidone. Risk of seizures increased with phenothiazines.
Side Effects
Side effects of Maprotiline Hydrochloride :
Common
Fatigue, Sedation, Lethargy, Weakness, Constipation, Dry mouth, Blurred vision
Less Common
Agitation, Anxiety, Headache, Insomnia, Nausea, Vomiting, Sweating
Infrequent
Orthostatic hypotension, ECG changes, tachycardia
Confusion, EPS, dizziness, paresthesia, tinnitus
Rash, Incr LFTs, Sexual dysfunction
Rare
Seizure, Agranulocytosis, Thrombocytopenia, Eosinophilia, Leukopenia, SIADH
Potentially Fatal: Seizures
Mode of Action
Maprotiline is a tetracyclic antidepressant pharmacologically similar to the tricyclic antidepressants. It's antidepressant effects appear to be due principally to inhibition of the re-uptake of noradrenaline at the neuronal membrane.
Note
Ludiomil 25mg Tablet generic name is Maprotiline Hydrochloride. Ludiomil 25mg Tablet is manufactured by Novartis (Bangladesh) Ltd.Ludiomil is availble in all over Bangladesh.
Mes BD drug index information on Ludiomil Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.