Lopadine Nasal Spray
Olopatadine 0.6% Nasal prep
0.6 gm/100 gm
Incepta Pharmaceuticals Ltd.
| Pack size | 120 metered dose (spray) in bot |
|---|---|
| Unite Price | 400 BDT |
Indications
Lopadine Nasal Spray is used for:
Allergic rhinitis
Adult Dose
Nasal
Seasonal allergic rhinitis
Adult: As 0.6% spray: 2 sprays into each nostril bid.
Child: 6-11 yr 1 spray into each nostril bid.
Child Dose
Nasal
Seasonal Allergic Rhinitis
<6 years: Safety and efficacy not established
6-12 years: 1 spray each nostril twice daily.
>12 years: 2 sprays each nostril twice daily.
Renal Dose
Administration
Priming: Before initial use, prime Nasal Spray by releasing 5 sprays or until a fine mist appears. When Nasal Spray has not been used for more than 7 days, re-prime by releasing 2 sprays.
Contra Indications
It is contraindicated incase of hypersensitivity to Olopatadine or to any component of the preparation.
Precautions
Patients should be informed to avoid spraying Nasal Spray in their eyes. Patient w/ other nasal disease. Patient Counselling May impair ability to engage in activities requiring complete mental alertness and motor coordination (e.g. driving or operating machinery) after admin of the nasal spray. Nasal examinations should be performed periodically for signs of adverse effects on the nasal mucosa.
Lactation: Unknown whether distributed in breast milk, caution advised
Pregnancy-Lactation
Interactions
May result in additive CNS depression w/ CNS depressants.
Side Effects
Side effects of Olopatadine 0.6% Nasal prep :
>10%
Bitter taste (12.8%; 1% pediatric), Respiratory epistaxis (3-25%)
1-10%
Headache (4.4%), Depression (2%), Fatigue (1%), Somnolence (1%), Weight gain (1%), Epistaxis (3.2%; 5.7% pediatric), Upper respiratory tract infection (2.6% pediatric), Pharyngolaryngeal pain (2.2%), Postnasal drip (1.5%), Cough (1.4%), Urinary tract infection (1.2%), Upper respiratory tract infection in children (3%)
<1%
CPK elevation, Dry mouth, Anosmia, Hyposmia, Nasopharyngitis, Throat irritation, Influenza
Mode of Action
Olopatadine is a relatively selective histamine H1-receptor antagonist which inhibits the release of histamine from mast cells and histamine-induced effects on conjunctival epithelial cells. It shares many of the pharmacologic effects of mast cell stabilisers.
Note
Lopadine 0.6 gm/100 gm Nasal Spray generic name is Olopatadine 0.6% Nasal prep. Lopadine 0.6 gm/100 gm Nasal Spray is manufactured by Incepta Pharmaceuticals Ltd.Lopadine is availble in all over Bangladesh.
Mes BD drug index information on Lopadine Nasal Spray is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.