Logibac 400 Capsule

Ceftibuten
400mg
Acme Laboratories Ltd.
Pack size
Unite Price 120.00 BDT

Indications

Logibac 400 Capsule is used for: Respiratory tract infections, Urinary tract infections

Adult Dose

Oral Respiratory tract infections, Urinary tract infections Adult: 400 mg once daily for 10 days.

Child Dose

Child: <6 months: Safety and efficacy not established 6-12 years old or <45 kg: 9 mg/kg PO qDay; 400 mg/day PO for 10 days maximum >12 years old or >45 kg: As in adults

Renal Dose

Renal impairment: CrCl (ml/min) 30-49 200 mg once daily. 5-29 100 mg once daily.

Administration

Susp: Should be taken on an empty stomach. Take 2 hr before or 1 hr after meals. Cap: May be taken with or without food.

Contra Indications

Hypersensitivity to cephalosporins.

Precautions

Hypersensitivity to penicillins; renal impairment; Porphyria. Monitor renal and haematologic status. Lactation: excretion in milk unknown; use with caution

Pregnancy-Lactation

Pregnancy Category: B Lactation: excretion in milk unknown; use with caution

Interactions

Enhanced nephrotoxicity of aminoglycosides. Increased serum concentration w/ probenecid. Decreased serum concentration w/ zinc salts.

Side Effects

Side effects of Ceftibuten : 1-10% Increased BUN (4%), Nausea (4%), Diarrhea (3%), Headache (3%), Increased eosinophils (3%), Decreased hemoglobin (2%), Dyspepsia (2%), Thrombocytosis (2%), Abdominal pain (1%), Dizziness (1%), Increased ALT (1%), Increased bilirubin (1%), Vomiting (1%) <1% Anorexia, Candidiasis, Constipation, Dysuria, Agitation, Fatigue, Insomnia, Irritability, Paresthesia, Rigors, Diaper rash, Urticaria, Dry mouth, Dyspnea, Nasal congestion, Increased transaminases, Increased creatinine, Leukopenia Potentially Fatal: Pseudomembranous colitis.

Mode of Action

Ceftibuten inhibits bacterial cell wall synthesis. It is stable to hydrolysis by many beta-lactamases and has greater activity than 1st or 2nd generation cephalosporins against gm-ve bacteria. It is less active in vitro than cefexime against S. pneumoniae.

Note

Logibac 400 400mg Capsule generic name is Ceftibuten. Logibac 400 400mg Capsule is manufactured by Acme Laboratories Ltd.Logibac 400 is availble in all over Bangladesh. Mes BD drug index information on Logibac 400 Capsule is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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