Lipofit IV Injectio
Purified Soybean Oil
10 gm/100 ml
Beacon Pharmaceuticals Ltd.
| Pack size | 500 ml bot |
|---|---|
| Unite Price | 1100.00 BDT |
Indications
Lipofit IV Injectio is used for:
Parenteral fat emulsions, essential fatty acid deficiency, Parenteral nutrition.
Adult Dose
1g triglycerides corresponds to 10 ml Intralipid 10%.
Adults. The recommended maximum dosage is 3 g triglycerides/kg body weight/day. Within this upper limit, Intralipid can be given to contribute up to 70% of the energy requirements, also in patients with highly increased energy requirements.
The infusion rate for Intralipid 10% should not exceed 500 ml in 5 hours.
Child Dose
1g triglycerides corresponds to 10 ml Intralipid 10%.
Neonates and infants. The recommended dosage range in neonates and infants is 0.5-4 g triglycerides/ kg bw/day.
The rate of infusion should not exceed 0.17 g triglycerides/kg bw/hour (4 g in 24 hours).
In prematures and low birthweight neonates, Intralipid should preferably be infused continuously over 24 hours. The initial dosage should be 0.5-1 g/kg bw/day followed by a successive increase by 0.5-1 g/kg bw/day up to 2g/kg bw/day.
Only with close monitoring of serum triglyceride concentration, liver tests and oxygen saturation may the dosage be increased to 4 g/kg bw/day. The rates given are maximum rates and no attempt should be made to exceed these in order to compensate for missed doses.
Renal Dose
Administration
Contra Indications
Intralipid is contraindicated in patients with acute shock and in patients with severe hyperlipemia. Severe liver insufficiency. Hemophagocytotic syndrome. Hypersensitivity to egg-, soya- or peanut protein or to any of the active substances or excipients.
Precautions
Intralipid should be given with caution in conditions of impaired lipid metabolism as in renal insufficiency, uncompensated diabetes mellitus, pancreatitis, impaired liver function, hypothyroidism (if hypertri-glyceridemic) and sepsis. If Intralipid is given to patients with these conditions, close monitoring of the serum triglyceride concentration is obligatory.
This medicinal product contains soya-bean oil and egg phospholipids, which may rarely cause allergic reactions. Cross allergic reactions have been observed between soybean and peanut.
Intralipid should be given with caution to neonates and prematures with hyperbilirubinemia and cases with suspected pulmonary hypertension. In neonates, particularly prematures on long term parenteral nutrition, platelet count, liver tests and serum triglyceride concentration should be monitored.
Intralipid may interfere with certain laboratory measurements (bilirubin, lactate dehydrogenase, oxygen saturation, Hb etc) if blood is sampled before fat has been adequately cleared from the blood stream. Fat is cleared after a fat free interval of 5-6 hours in most patients.
Pregnancy-Lactation
Interactions
Side Effects
Side effects of Purified Soybean Oil :
Intralipid infusion may cause a rise in body temperature and, less frequently, shivering, chills and nausea/vomiting (incidence<1%).
Mode of Action
Note
Lipofit 10 gm/100 ml IV Injectio generic name is Purified Soybean Oil. Lipofit 10 gm/100 ml IV Injectio is manufactured by Beacon Pharmaceuticals Ltd.Lipofit is availble in all over Bangladesh.
Mes BD drug index information on Lipofit IV Injectio is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.