Indications
Kestine Tablet is used for:
Allergic rhinitis, Allergic conditions, Chronic idiopathic urticaria
Adult Dose
Oral
Allergic conditions
Adult: 10-20 mg once daily.
Child Dose
Oral
Allergic conditions
Child: >6 yr: 5 mg once daily.
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Hypersensitivity, cardiac arrhythmias.
Precautions
Caution is advised when used in hepatic impairment, renal insufficiency, QTc interval prolongation. Pregnancy, lactation.
Pregnancy-Lactation
Interactions
Concomitant use of ketoconazole, itraconazole, clarithromycin or erythromycin may increase plasma levels of ebastine and cause QTc interval prolongation.
Side Effects
Side effects of Ebastine :
Headache, dry mouth, drowsiness, pharyngitis, abdominal pain, dyspepsia, asthenia, epistaxis, rhinitis, sinusitis, nausea, insomnia.
Mode of Action
Ebastine, a piperidine derivative, is a long-acting, nonsedating, second-generation histamine receptor antagonist that binds preferentially to peripheral H1 receptors. It is metabolised to active metabolite, carebastine. It has antihistaminic, antiallergic activity and prevents histamine-induced bronchoconstriction. It does not have significant sedative or antimuscarinic actions.
Note
Kestine 10mg Tablet generic name is Ebastine. Kestine 10mg Tablet is manufactured by Synovia Pharma PLC.Kestine is availble in all over Bangladesh.
Mes BD drug index information on Kestine Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.