Indications
Ilodon Tablet is used for:
Schizophrenia
Adult Dose
Schizophrenia
Day 1: 1 mg PO q12hr; increase qDay to effective dose of 6-12 mg PO q12hr
Day 2: 2 mg PO q12hr, THEN increase qDay by 2 mg/day to effective dose of 6-12 mg PO q12hr; not to exceed 24 mg/day
Must gradually increase dose to avoid orthostatic hypotension
Hepatic impairment
Mild: No dosage adjustment required
Moderate: Caution advised
Severe: Use not recommended
Child Dose
Safety and efficacy not established
Renal Dose
Renal impairment: Unlikely to have a significant impact since <1% of drug is excreted unchanged in urine
Administration
Contra Indications
Hypersensitivity.
Precautions
This drug is not approved for the treatment of patients with dementia-related psychosis.
Prolongs QT interval; caution with other drugs/conditions that increase QTc.
Not recommended in hepatic impairment.
Risk of neuroleptic malignant syndrome and extrapyramidal symptoms.
May cause anticholinergic side effects (eg., confusion, agitation).
Blood dyscrasias (leukopenia, neutropenia, agranulocytosis) may occur.
Orthostatic hypotension may occur.
Lactation: not known if excreted in breast milk, do not nurse
Pregnancy-Lactation
Pregnancy Category: C
Neonates exposed to antipsychotic drugs during the 3rd trimester of pregnancy are at risk for extrapyramidal and/or withdrawal symptoms following delivery
These complications vary in severity; in some cases, symptoms have been self-limited, while in other cases neonates have required intensive care unit support and prolonged hospitalization
Lactation: not known if excreted in breast milk, do not nurse
Interactions
Side Effects
Side effects of Iloperidone :
>10%
Dizziness (20%), Dry mouth (15%), Nausea (10%), Somnolence (10%), Tachycardia (12%)
1-10% (selected)
Diarrhea, Ejaculation failure, Myalgia, Nasal congestion, Orthostatic hypotension, Palpitations, Urinary incontinence, Weight gain
Frequency Not Defined (selected)
Priapism
Mode of Action
May act by antagonizing a combination of dopamine type 2 (D2) and serotonin type 2 (5-HT2) receptors.
Alpha blocker.
Note
Ilodon 2mg Tablet generic name is Iloperidone. Ilodon 2mg Tablet is manufactured by Beacon Pharmaceuticals Ltd.Ilodon is availble in all over Bangladesh.
Mes BD drug index information on Ilodon Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.