Human Anti-tetanus Immuno Globulin Injection
Tetanus (Human Anti-tetanus) Immunoglobulin
250 IU
CSL Behring GmbH, Germany
| Pack size | |
|---|---|
| Unite Price | 1200 BDT |
Indications
Human Anti-tetanus Immuno Globulin Injection is used for:
1. Prophylaxis of tetanus, following injury in patients whose immunization is incomplete or uncertain.
2. Therapeutically in the, treatment of tetanus.
Tetanus immunoglobulin should always be administered in conjunction with an active tetanus vaccination unless there are contraindications or confirmations of adequate vaccination.
Adult Dose
Intramuscular
Post-exposure prophylaxis of tetanus: For adults single dose of 250 IU should be given.
The dose may be increased to 500 IU in case of:
1. Infected wounds where surgically appropriate treatment cannot be achieved within 24 hours.
2. Deep or contaminated wounds with tissue damage and reduced oxygen supply, as well as foreign body injury (e.g., bites, stings or shots),
3. Burns, congelations,
4. Tissue necrosis,
5. Septicaemic abortion,
6. Adults weighing more than the average.
In case of extensive burns, it is advisable to administer a second injection of 250 IU human tetanus immunoglobulin after the exsudative phase of the burn has subsided (about 36 hours after onset of the burn). At the same time, 0.5ml of tetanus vaccine in a different extremity with a separate syringe and complete immunization schedule is required to be administered.
Therapy of clinically manifest tetanus: For adults and children single doses of 3,000 to 6,000 IU (in combination with other appropriate clinical procedures).
Child Dose
Intramuscular
Post-exposure prophylaxis of tetanus: For children single dose of 250 IU should be given.
The dose may be increased to 500 IU in case of:
1. Infected wounds where surgically appropriate treatment cannot be achieved within 24 hours.
2. Deep or contaminated wounds with tissue damage and reduced oxygen supply, as well as foreign body injury (e.g., bites, stings or shots),
3. Burns, congelations,
4. Tissue necrosis,
5. Septicaemic abortion,
6. Adults weighing more than the average.
In case of extensive burns, it is advisable to administer a second injection of 250 IU human tetanus immunoglobulin after the exsudative phase of the burn has subsided (about 36 hours after onset of the burn). At the same time, 0.5ml of tetanus vaccine in a different extremity with a separate syringe and complete immunization schedule is required to be administered.
Therapy of clinically manifest tetanus: For adults and children single doses of 3,000 to 6,000 IU (in combination with other appropriate clinical procedures).
Renal Dose
Administration
This vaccine should only be administered by intramuscular injection. Human tetanus immunoglobulin should not be administered by intravenously.
Contra Indications
Hypersensitivity homologous Ig-containing medicinal products particularly in patients w/ IgA deficiency & concurrent presence of Ab to IgA.
Precautions
Caution when used in patients with coagulation disorders or thrombocytopenia. Not to be used for IV admin. Pregnancy, lactation. If adsorbed tetanus vaccine is to be used concurrently, the vaccine and immunoglobulin should be administered with separate syringes and into different inj sites with separate lymphatic drainage. Patients should be observed for at least 20 minutes after admin.
Pregnancy-Lactation
Pregnancy Category: C
Lactation: not known if excreted in breast milk, no adverse effects reported
Interactions
May reduce the efficacy of live vaccines.
Side Effects
Side effects of Tetanus (Human Anti-tetanus) Immunoglobulin :
Inj-site reactions: Pain, soreness and tenderness. Increased temperature, angioneurotic oedema, nephritic syndrome, anaphylactic shock.
Mode of Action
Tetanus immunoglobulin is used for passive immunisation against tetanus.
Note
Human Anti-tetanus Immuno Globulin 250 IU Injection generic name is Tetanus (Human Anti-tetanus) Immunoglobulin. Human Anti-tetanus Immuno Globulin 250 IU Injection is manufactured by CSL Behring GmbH, GermanyHuman Anti-tetanus Immuno Globulin is availble in all over Bangladesh.
Mes BD drug index information on Human Anti-tetanus Immuno Globulin Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.