Histacet Syrup

Cetirizine
5mg/5ml
Medimet Pharmaceuticals Ltd.
Pack size 50ml bot
Unite Price 15.50 BDT

Indications

Histacet Syrup is used for: Allergic rhinitis, Hay fever, Allergies, Urticaria

Adult Dose

Oral Allergic conditions Adult: 10 mg once daily or 5 mg bid. Elderly: Initially, 5 mg once daily. Hepatic impairment: Initially, 5 mg once daily. Syrup: Adults: 2 teaspoon once daily or 1 teaspoon twice daily.

Child Dose

Oral Allergic conditions Child: 6-23 mth 2.5 mg once daily increased to max of 2.5 mg bid in childn >12 mth; 2-5 yr 5 mg once daily or in 2 divided doses; >6 yr 10 mg once daily or in 2 divided doses. Syrup: Children over 6 years: 2 teaspoon once daily or 1 teaspoon twice daily. Children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoon twice daily. <2 years: Safety and efficacy not established

Renal Dose

Renal impairment GFR >50 mL/min: Dose adjustment not necessary GFR< 50 mL/min: 5 mg PO qDay Peritoneal dialysis: 5 mg PO qDay Intermittent hemodialysis: 5 mg PO qDay; may also administer 3 times weekly

Administration

May be taken with or without food.

Contra Indications

Hypersensitivity; lactation.

Precautions

Hepatic or renal impairment; elderly; tasks requiring mental alertness eg, driving or operating heavy machinery; pregnancy. Lactation: Excreted in breast milk; use not recommended

Pregnancy-Lactation

Pregnancy There are no adequate and well-controlled studies in pregnant women Lactation Cetirizine has been reported to be present in human breast milk In mice and beagle dogs, studies indicated that cetirizine was excreted in milk When a drug is present in animal milk, it is likely it will be present in human milk

Interactions

Additive CNS depression when administered concomitantly w/ other CNS depressants (e.g. sedatives, tranquilisers).

Side Effects

Side effects of Cetirizine : >10% Somnolence (2-14%), Headache (11-14%) 1-10% Fatigue (5.9%), Dry mouth (5%), Dizziness (2%), Diarrhea (2-3%), Malaise (4%), Bronchospasm (2-3%), Vomiting (2-3%), Epistaxis (2-4%) <1% Stomach pain, Drowsiness, Angioedema, Fussiness, Hallucinations, Hypotension, Tremor, Tongue discoloration

Mode of Action

Cetirizine is a potent and highly selective antagonist of the peripheral histamine H1-receptor on effector cells in the GI tract, blood vessels and resp tract.

Note

Histacet 5mg/5ml Syrup generic name is Cetirizine. Histacet 5mg/5ml Syrup is manufactured by Medimet Pharmaceuticals Ltd.Histacet is availble in all over Bangladesh. Mes BD drug index information on Histacet Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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