Haemaccel Injection
Polygeline + Calcium Chloride + Potassium Chloride + Sodium Chloride
Renata Limited
| Pack size | |
|---|---|
| Unite Price | 700.00 BDT |
Indications
Haemaccel Injection is used for:
As a plasma volume substitute in the initial treatment of,
1. hypovolaemic shock, due to:
a) Haemorrhage (visible or concealed)
b) Burns, peritonitis, pancreatitis, crush injuries
2. Fluid replacement in plasma exchange
3. Extra-corporeal circulation
4. Isolated organ perfusion
5. As a carrier solution for insulin
Adult Dose
Intravenous infusion
Should be administered intravenously in a volume approximately equal to the estimated blood loss.
The rate of infusion is determined by the condition of the patient.
Normally, 500 ml will be infused in not less than 60 minutes but in emergencies this can be rapidly infused. Losses of up to 25 % of the blood volume can be replaced by this alone.
Hypovolaemic shock:
500 -1,000 ml this fluid preparation should be infused intravenously initially.
Up to 1,500 ml blood loss can be replaced entirely by this fluid preparation.
For between 1,500 ml and 4,000 ml blood loss, fluid replacement should be with equal volumes of this fluid preparation and blood given separately.
Burns:
It is suggested that at least 1 ml this fluid preparation be infused per kg of body weight. Multiplied by the % of body surface burned for each 24 hours for two days. Additional crystalloid solutions should be given to cover the normal fluid loss
Child Dose
Renal Dose
Administration
Should be administered intravenously.
Contra Indications
Contra-indicated in patients with a known hypersensitivity to constituents of the preparation and/or patients with existing anaphylactoid reactions.
Precautions
All conditions in which an increase in intravascular volume and its consequences (e.g. increased stroke volume, elevated blood pressure), or an increase in interstitial fluid volume, or haemodilution could represent a special risk for the patient. Examples of such conditions are: congestive heart failure, hypertension, oesophageal varices, pulmonary oedema, haemorrhagic diathesis, renal and post-renal anuria.
In all patients at an increased risk of histamine release (e.g. allergic persons and patients with a history of histamine response; also patients who in the previous 7 days have received a drug which releases histamine). In the latter cases, Haemaccelmay be given only after taking appropriate prophylactic steps. Reactions caused by histamine release can be avoided by the prophylactic use of H1 and H2 receptor antagonists.
Pregnancy-Lactation
Haemorrhage around the time of childbirth or blood loss during other obstetric or gynaecological procedures may necessitate plasma volume replacement. This fluid preparations has been used for many years for the initial treatment in such cases without apparent ill consequence.
If plasma volume replacement is needed during pregnancy, this fluid preparations may be used if blood is not available.
Interactions
This contains calcium ions and caution should be observed in patients being treated with cardiac glycosides. Haemaccel may be mixed with other infusion solutions (e.g. saline, dextrose, Ringer's solution etc.) or with heparinised blood. Sterility must be maintained. Compatible water-soluble drugs may be infused in Haemaccel, e.g. insulin, streptokinase etc. Any additive should be injected into the bottle through a small hole located next to the pull-ring.
Side Effects
Side effects of Polygeline + Calcium Chloride + Potassium Chloride + Sodium Chloride :
During or after the infusion of volume-expanding solutions, transient urticarial skin reactions (wheals), hypotension, tachycardia, bradycardia, nausea/vomiting, dyspnoea, increases in temperature and/or shivering may occasionally occur.
Rare cases of severe hypersensitivity reactions including shock have been observed.
Histamine release has been shown to be a cause of anaphylactic side-effects associated with this infusions.
Mode of Action
This is a gelatin derivative with a mean molecular weight of 30,000 Dalton. It is iso-oncotic with plasma and has a viscosity and pH similar to plasma. It has very little pharmacological action and does not interfere with cross matching or blood typing tests.
Note
Haemaccel Injection generic name is Polygeline + Calcium Chloride + Potassium Chloride + Sodium Chloride. Haemaccel Injection is manufactured by Renata LimitedHaemaccel is availble in all over Bangladesh.
Mes BD drug index information on Haemaccel Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.