H-Trimazole Cream
Clotrimazole 1% + Hydrocortisone 1% Topical
1 gm + 1 gm/100 gm
Opsonin Pharma Limited
| Pack size | 10gm,20gm tube |
|---|---|
| Unite Price | 35.63,55.00 BDT |
Indications
H-Trimazole Cream is used for:
Athlete's foot, Tinea pedis, Candida nappy rash, Fungal infections, Jock itch, Ringworm, Tinea cruris, Tinea corporis
Adult Dose
Topical/Cutaneous
Inflammatory skin fungal infections
Adult: As cream: Apply thinly and evenly to the affected area bid and rub in gently. Max duration: 7 days.
Max: 10 mg/kg; 500 mg for 50 kg adult equivalent to approx 2 cm to be divided into 2 applications per day.
Elderly: Use minimum quantity for the shortest duration.
Child Dose
Child: Require shorter course of treatment.
Renal Dose
Administration
Contra Indications
Hypersensitivity.
Precautions
Avoid contact with eyes upon topical application. Childn <3 yrs. Pregnancy, lactation.
Pregnancy-Lactation
Interactions
Antagonism with polyene antibiotics.
Thiazides may enhance hyperglycaemia and hypokalaemia caused by corticosteroids. Increased incidence of peptic ulcer or GI bleeding with concurrent NSAIDs admin. Response to anticoagulants altered. Dose of antidiabetics and antihypertensives needs to be increased. Decreases serum conc of salicylates and antimuscarinic agents. Ethanol may enhance gastric mucosal irritation. Reduced efficacy with concurrent use of carbamazepine, phenytoin, primidone, barbiturates and rifampicin. Mutual inhibition of metabolism between ciclosporin and corticosteroids increase plasma conc of both drugs. Enhanced effect in women taking oestrogens or oral contraceptives.
Side Effects
Side effects of Clotrimazole 1% + Hydrocortisone 1% Topical :
Topical: Erythema, stinging, irritation; hypersensitivity reactions; contact dermatitis.
Mode of Action
Clotrimazole is a broad-spectrum antifungal which binds to phospholipids in the cell membrane altering cell wall permeability causing a loss in essential intracellular elements.
Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It may also be used as replacement therapy in adrenocortical insufficiency.
Note
H-Trimazole 1 gm + 1 gm/100 gm Cream generic name is Clotrimazole 1% + Hydrocortisone 1% Topical. H-Trimazole 1 gm + 1 gm/100 gm Cream is manufactured by Opsonin Pharma LimitedH-Trimazole is availble in all over Bangladesh.
Mes BD drug index information on H-Trimazole Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.