Galvus Tablet

Vildagliptin
50mg
Novartis Pharma AG, Switzerland
Pack size 28's pack
Unite Price 31.50 BDT

Indications

Galvus Tablet is used for: Type 2 DM

Adult Dose

Oral Type 2 diabetes mellitus Adult: 50 mg bid. Not recommended to use >100 mg/day. W/ metformin or a thiazolidinedione: 50 mg twice daily; w/ a sulfonylurea: 50 mg/day in the morning.

Child Dose

Renal Dose

Renal impairment: Moderate, severe and ESRD: 50 mg once daily.

Administration

May be taken with or without food.

Contra Indications

Hypersensitivity to vildagliptin

Precautions

Patient w/ cardiac failure (NYHA functional class IV), type 1 DM; history of acute pancreatitis. Not intended for the treatment of diabetic ketoacidosis. Hepatic impairment, including patients w/ pre-treatment ALT or AST >3 times the upper limit of normal (ULN). Moderate or severe renal impairment, ESRD. Monitoring Parameters Monitor liver function.

Pregnancy-Lactation

Interactions

Decreased hypoglycaemic effect w/ thiazides, corticosteroids, thyroid products and sympathomimetics.

Side Effects

Side effects of Vildagliptin : Nausea, peripheral oedema, headache, tremor, asthenia, dizziness, constipation, hypoglycaemia, arthralgia, hepatic dysfunction, nasopharyngitis, upper resp tract infection, pancreatitis, exfoliative and bullous skin reactions.

Mode of Action

Vildagliptin is a dipeptidylpeptidase-4 (DPP-4) inhibitor that improves glycaemic control by preventing DPP-4 from inactivating the incretin hormones glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide, thus prolonging incretin activity in response to ingestion of nutrients. This increases insulin sensitivity, decreases glucagon secretion and improves ?-cell function.

Note

Galvus 50mg Tablet generic name is Vildagliptin. Galvus 50mg Tablet is manufactured by Novartis Pharma AG, SwitzerlandGalvus is availble in all over Bangladesh. Mes BD drug index information on Galvus Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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