Fulvestrant Ever Pharma Injection
Fulvestrant
250 mg
ZAS Corporation
| Pack size | 2 pre-filled syringe (5 ml) in a box |
|---|---|
| Unite Price | 50000.00 BDT |
Indications
Fulvestrant Ever Pharma Injection is used for:
Metastatic breast cancer, in postmenopausal women w/ oestrogen-receptor positive tumours.
Adult Dose
Intramuscular
Metastatic breast cancer in postmenopausal women with oestrogen-receptor positive tumours
Adult: 500 mg (250 mg into each buttock) on days 1, 15, and 29, then once monthly thereafter.
Moderate (Child-Pugh Class B): 250 mg (into 1 buttock) on days 1, 15, and 29, then once monthly thereafter.
Severe: Contraindicated.
Child Dose
Renal Dose
Renal impairment
Negligible amounts of fulvestrant are eliminated in urine
In clinical trials, fulvestrant concentrations in women with eCrCl ?30 mL/min were similar to women with normal creatinine
Administration
Contra Indications
Pregnancy and lactation.
Precautions
Patient w/ bleeding diatheses, thrombocytopenia. Admin at dorsogluteal inj site. Mild to moderate hepatic and severe renal (CrCl <30 mL/min) impairment.
Pregnancy-Lactation
Interactions
Increased risk of bleeding when taken concomitantly w/ anticoagulants.
Side Effects
Side effects of Fulvestrant :
>10%
Nausea (26%)
Asthenia (23%)
Pain (19%)
Vasodilatation (18%)
Pharyngitis (16%)
HA (15%)
Back pain (14%)
Constipation (13%)
Vomiting (13%)
Abd pain (12%)
Diarrhea (12%)
Inj site pain (11%)
1-10%
Cough (10%)
Anorexia (9%)
Peripheral edema (9%)
Chest pain (7%)
Flu-like syndrome (7%)
Rash (7%)
Depression (6%)
Fever (6%)
UTI (6%)
Anemia (5%)
<1%
Angioedema
Leukopenia
Myalgia
Thrombosis
Osteoporosis
Mode of Action
Fulvestrant competitively binds to oestrogen receptors, forming a nuclear complex, leading to down-regulation of oestrogen receptor protein levels and inhibition of tumour growth.
Note
Fulvestrant Ever Pharma 250 mg Injection generic name is Fulvestrant. Fulvestrant Ever Pharma 250 mg Injection is manufactured by ZAS CorporationFulvestrant Ever Pharma is availble in all over Bangladesh.
Mes BD drug index information on Fulvestrant Ever Pharma Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.