Ficef Capsule

Cefadroxil
500mg
Unimed & Unihealth Manufacturers Ltd.
Pack size 20's pack
Unite Price 12.00 BDT

Indications

Ficef Capsule is used for: Pharyngitis, Susceptible infections, Sore throat, Tonsillitis, Urinary tract infection, Reproductive tract infection, Skin infections

Adult Dose

Oral Tonsillitis; Skin and skin structure infections; Streptococcal pharyngitis; Urinary tract infections Adult: 1-2 g daily as a single or in 2 divided doses. Hepatic impairment: No dosage adjustment needed.

Child Dose

Oral Tonsillitis; Skin and skin structure infections; Streptococcal pharyngitis; Urinary tract infections Child: >6 yr <40 kg: 30-50 mg/kg daily as a single or in 2 divided doses, up to 100 mg/kg daily.

Renal Dose

Renal impairment: CrCl (ml/min) 26-50 0.5-1 g bid. 11-25 0.5-1 g once daily. <10 0.5-1 g every 36 hr.

Administration

May be taken with or without food. May be taken w/ meals to reduce GI discomfort.

Contra Indications

Hypersensitivity to cephalosporins.

Precautions

Impaired renal function; pregnancy and lactation. Lactation: enters breast milk; use with caution

Pregnancy-Lactation

Pregnancy Category: B Lactation: enters breast milk; use with caution

Interactions

Concomitant use w/ bacteriostatic antibiotics (e.g. tetracycline, erythromycin, sulfonamides, chloramphenicol) may cause antagonistic effect. May potentiate nephrotoxic effects of aminoglycoside antibiotics, polymyxin B, colistin or high-dose loop diuretics. May enhance the anticoagulant effect of vit K antagonists. May diminish the therapeutic effect of BCG, typhoid vaccine and Na picosulfate. May attenuate the effect of oral contraceptives. Increased serum concentration w/ probenecid. Reduced bioavailability w/ colestyramine.

Side Effects

Side effects of Cefadroxil : 1-10% Diarrhea <1% Abdominal pain, Dyspepsia, Nausea, Vomiting, Rash, Urticaria, Pseudomembranous colitis, Stevens-Johnson syndrome, Anaphylaxis, Transaminases increased, Neutropenia Potentially Fatal: Anaphylactic reaction; pseudomembranous colitis.

Mode of Action

Cefadroxil binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death. Cefadroxil is not active against Proteus, Pseudomonas, Enterobacter, Morganella, Serratia and Listeria monocytogenes.

Note

Ficef 500mg Capsule generic name is Cefadroxil. Ficef 500mg Capsule is manufactured by Unimed & Unihealth Manufacturers Ltd.Ficef is availble in all over Bangladesh. Mes BD drug index information on Ficef Capsule is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Cefadroxil :

Capsule
Adocil 500mg
Kemiko Pharmaceuticals Ltd.
Powder for Suspension
Arocef 125mg/5ml
Eskayef Pharmaceuticals Ltd.
Capsule
Arocef 500mg
Eskayef Pharmaceuticals Ltd.
Paediatric Drops
Cefador 125mg/1.2ml
Somatec Pharmaceuticals Ltd.
Powder for Suspension
Cefador 125mg/5ml
Somatec Pharmaceuticals Ltd.