Eudaxen Tablet
Diazoxide
50mg
Everest Pharmaceuticals Ltd.
| Pack size | 100s in HDPE container |
|---|---|
| Unite Price | 150.00 BDT |
Indications
Eudaxen Tablet is used for:
Hypoglycaemia
Adult Dose
Oral
Hypoglycaemia
Adult: Initially, 3-5 mg/kg daily in 2 or 3 divided doses.
Maintenance: 3-8 mg/kg daily up to 10-15 mg/kg daily in patients w/ refractory hypoglycaemia or insulinoma.
Child Dose
Oral
Hypoglycaemia
Child: Neonates: Initially, 5 mg/kg bid.
Maintenance: 1.5-3 mg/kg bid or tid up to 7 mg/kg tid may be required in some cases.
>1 mth Initially, 1.7 mg/kg tid.
Maintenance: 1.5-3 mg/kg bid or tid up to 5 mg/kg tid may be required in some cases.
Renal Dose
Renal Impairment
Dose reductions may be necessary.
Administration
Contra Indications
Hypersensitivity to diazoxide, thiazides, or sulfonamide derivatives
Precautions
Patient in whom retention of Na and water may be hazardous (e.g. impaired cardiac or cerebral circulation); patient w/ aortic coarctation, arteriovenous shunt, heart failure or other cardiac disorders in which increase in cardiac output could be detrimental; hyperuricaemia or history of gout; patient w/ risk factors for pulmonary HTN. Renal impairment. Pregnancy and lactation.
Pregnancy-Lactation
Pregnancy Category: C
Lactation: Excretion in milk unknown; not recommended
Interactions
Enhanced hyperglycaemic, hyperuricemic or hypotensive effects w/ diuretics. Increased risk of hypotension w/ other antihypertensive drugs or vasodilators. Increased risk of hyperglycaemia w/ concomitant phenytoin, corticosteroids or oestrogen-progestogen combinations. May displace other highly protein-bound drugs (e.g. coumarin and its derivatives) resulting in higher blood levels of these substances.
Side Effects
Side effects of Diazoxide :
Frequency Not Defined
Angina
Cardiac arrest
Anxiety
Fever
Polyneuritis
CHF
Hypotension
Palpitation
Tachycardia
Dizziness
Anorexia
Abdominal pain
Constipation
Diarrhea
Loss of taste
Nausea
Vomiting
Diabetic ketoacidosis
Hirsutism
Scalp hair loss
Hyperglycemia
Sodium and fluid retention
Mode of Action
Diazoxide increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the β-cells of the pancreas, and may increase the hepatic output of glucose. When given IV, it produces a fall in BP by causing vasodilation of the arterioles, thus a reduction in peripheral resistance. It has an antidiuretic action and produces fluid and electrolyte retention.
Note
Eudaxen 50mg Tablet generic name is Diazoxide. Eudaxen 50mg Tablet is manufactured by Everest Pharmaceuticals Ltd.Eudaxen is availble in all over Bangladesh.
Mes BD drug index information on Eudaxen Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.