Indications
Epastat Tablet is used for:
Diabetic neuropathy
Adult Dose
Oral
Diabetic neuropathy
Adult: 50 mg tid.
Child Dose
Renal Dose
Administration
Contra Indications
Hypersensitivity. Pregnant or breastfeeding.
Precautions
Urine may turn yellowish brown or reddish after taking the medicine, because the yellowish brown or reddish color is attributed to components of this medicine.
Pregnancy-Lactation
Interactions
Side Effects
Side effects of Epalrestat :
The most commonly reported adverse reactions include abdominal pain, nausea, rash, itch, erythema and blister.
Mode of Action
Epalrestat is aldose reductase inhibitor. The aldose reductase inhibitors have a distinct mechanism of action, affecting the underlying disease process in diabetic neuropathy, although the extent of the polyol pathway involvement is yet to be determined. Epalrestat reduces sorbitol accumulation in the sciatic nerve, erythrocytes. Epalrestat may improve motor and sensory nerve conduction velocity and subjective neuropathy symptoms.
Note
Epastat 50 mg Tablet generic name is Epalrestat. Epastat 50 mg Tablet is manufactured by Opsonin Pharma LimitedEpastat is availble in all over Bangladesh.
Mes BD drug index information on Epastat Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.