Edopain ER Tablet
Etodolac
600mg
Incepta Pharmaceuticals Ltd.
| Pack size | 20's pack |
|---|---|
| Unite Price | 18.00 BDT |
Indications
Edopain ER Tablet is used for:
Rheumatoid arthritis, Pain, Osetoarthritis
Adult Dose
Oral
Osteoarthritis; Rheumatoid arthritis
Adult: 600-1000 mg/day in divided doses adjusted according to response. Max: 1200 mg/day.
ER tablet: Once daily
Hepatic impairment: Dose adjustment not necessary
Child Dose
Juvenile Rheumatoid Arthritis
<6 years
Safety and efficacy not established
6-16 years
20-30 kg (extended release): 400 mg PO once daily
31-45 kg (extended release): 600 mg PO once daily
46-60 kg (extended release): 800 mg PO once daily
>60 kg (extended release): 1000 mg PO once daily
Renal Dose
Mild-to-moderate renal impairment: Dose adjustment not necessary
Severe renal impairment; Not recommended
Administration
Should be taken with food. Take w/ or immediately after meals.
Contra Indications
Peptic ulcer, hypersensitivity to etodolac/NSAIDs. Childn; pregnancy (3rd trimester) and lactation.
Precautions
CHF, dehydration, impaired renal, hepatic function, history of GI disease. Elderly, patients receiving anticoagulant.
Lactation: Unknown whether drug is excreted in breast milk; not recommended
Pregnancy-Lactation
Pregnancy category: C; avoid in late pregnancy (may cause premature closure of ductus arteriosus)
Lactation: Unknown whether drug is excreted in breast milk; not recommended
Interactions
Increased effect of warfarin, lithium, methotrexate, digoxin, cyclosporin, aspirin. Effect may be reduced with aspirin. Reduced effect of some diuretics and ?-blockers. Alcohol enhances gastric mucosal irritation.
Side Effects
Side effects of Etodolac :
1-10%
Dyspepsia (10%), Dizziness (3-9%), Nervousness (1-3%), Pruritus (1-3%), Blurred vision (1-3%), Depression (1-3%), Chills/fever (1-3%)
>1%
Asthenia, malaise, Blurred vision, Bronchospasm, Dysuria, urinary frequency, Edema, Melena, Rash, Tinnitus
Potentially Fatal: Acute renal failure; blood disorder; nephrotoxicity; angioedema, arrhythmia, bone marrow suppression, CHF, dyspnoea, erythema multiforme, exfoliative dermatitis, hepatitis, hypertension, peripheral neuropathy, Stevens-Johnson syndrome, syncope, tachycardia, toxic amblyopia, toxic epidermal necrolysis, urticaria.
Mode of Action
Etodolac is an NSAID derived from pyrano-indoleacetic acid, inhibits cyclooxygenase 2 (COX-2) resulting in decreased prostaglandin precursor formation.
Note
Edopain ER 600mg Tablet generic name is Etodolac. Edopain ER 600mg Tablet is manufactured by Incepta Pharmaceuticals Ltd.Edopain ER is availble in all over Bangladesh.
Mes BD drug index information on Edopain ER Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.