Ectover 6 Tablet
Ivermectin
6mg
Goodman Pharmaceuticals Ltd.
| Pack size | 10's Pack |
|---|---|
| Unite Price | 10.00 BDT |
Indications
Ectover 6 Tablet is used for:
Ascariasis, Strongyloidiasis, Filariasis, Scabies, Onchocerciasis, Gnathostomiasis
Adult Dose
Strongyloidiasis of the Intestinal Tract
15-24 kg: 3 mg PO once
25-35 kg: 6 mg PO once
36-50 kg: 9 mg PO once
51-65 kg: 12 mg PO once
66-79 kg: 15 mg PO once
>80 kg: 200 mcg/kg PO once
River Blindness (Onchocerciasis)
15-25 kg: 3 mg PO; may repeat in 3-12 mo
26-44 kg: 6 mg PO; may repeat in 3-12 mo
45-64 kg: 9 mg PO; may repeat in 3-12 mo
65-84 kg: 12 mg PO; may repeat in 3-12 mo
>85 kg: 150 mcg/kg PO; may repeat in 3-12 mo
Scabies Due to Sarcoptes Scabiel
200 mcg/kg as single dose; may repeat in 14 days if necessary
Gnathostoma Spinigerum
Gnathostomiasis: 200 mcg/kg as single dose
Child Dose
River Blindness (Onchocerciasis)
<15 kg: Safety and efficacy not established
15-25 kg: 3 mg PO; may repeat in 3-12 mo
26-44 kg: 6 mg PO; may repeat in 3-12 mo
45-64 kg: 9 mg PO; may repeat in 3-12 mo
65-84 kg: 12 mg PO; may repeat in 3-12 mo
>85 kg: 150 mcg/kg PO; may repeat in 3-12 mo
Strongyloidiasis of the Intestinal Tract
<15 kg: Safety and efficacy not established
15-24 kg: 3 mg PO once
25-35 kg: 6 mg PO once
36-50 kg: 9 mg PO once
51-65 kg: 12 mg PO once
66-79 kg: 15 mg PO once
>80 kg: 200 mcg/kg PO once
Scabies
Child: >15 kg: Sarcoptes scabiei 200 mcg/kg as a single dose, repeat dose in 2 wk.
Renal Dose
Administration
Oral
Should be taken on an empty stomach.
Contra Indications
Hypersensitivity. Pregnancy and lactation. Childn <15 kg body weight.
Precautions
Concurrent Loa loa infection, impaired blood-brain barrier function due to infection.
Lactation: Enters breast milk (AAP Committee states compatible with nursing)
Pregnancy-Lactation
Pregnancy category: C
Pregnancy
There are no studies in pregnant women; epidemiologic studies during pregnancy are insufficient to inform a drug-associated risk of adverse developmental outcomes, because either the timing of administration during gestation was not accurately ascertained or the administration occurred only during the second trimester; however, systemic exposure from topical use of ivermectin is much lower than that from oral use
In animal reproduction studies, ivermectin induced adverse developmental outcomes when orally administered to pregnant mice, rats and rabbits during the period of organogenesis only at or near doses that were maternally toxic to the pregnant females
Lactation
There is information available on the presence of ivermectin in human milk in 4 lactating women after a single 150 mcg/kg oral dose of ivermectin; however, there is insufficient information from this study to determine effects of ivermectin on breastfed infant or on milk production
Topical ivermectin systemic exposure is much lower than that for oral ivermectin; furthermore, amount of ivermectin present in human milk after topical application to lactating women has not been studied
The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for therapy and any potential adverse effects on breastfed infant or from underlying maternal condition
Lactation: Enters breast milk (AAP Committee states compatible with nursing)
Interactions
Bioavailability may be increased by alcohol, levamisole.
Side Effects
Side effects of Ivermectin :
Diarrhoea, nausea, vomiting, dizziness, pruritus, urticaria, rash, arthralgia, fever, myalgia, asthenia, postural hypotension, tachycardia, oedema, lymphadenopathy, sore throat, cough, headache, somnolence, transient eosinophilia, raised liver enzyme values.
Mode of Action
Ivermectin selectively binds and with high affinity to glutamate-gated chloride ion channels, which occur in invertebrate nerve and muscle cells leading to an increase in the permeability of cell membranes to chloride ions with hyperpolarization of the nerve or muscle cell and, ultimately, death of the parasite.
Note
Ectover 6 6mg Tablet generic name is Ivermectin. Ectover 6 6mg Tablet is manufactured by Goodman Pharmaceuticals Ltd.Ectover 6 is availble in all over Bangladesh.
Mes BD drug index information on Ectover 6 Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.