Dyvon Plus Topical Suspension

Betamethasone 0.05% + Calcipotriol 0.005% topical

50 mg + 5 mg/100 gm

Square Pharmaceuticals Ltd.

Pack size	25ml bot
Unite Price	551.65 BDT

Indications

Dyvon Plus Topical Suspension is used for: Psoriasis

Adult Dose

Adult: Topical : >18 yr: Apply once daily up to 4 wk. Max: 100 g/wk.

Child Dose

Renal Dose

Administration

Contra Indications

Known or suspected disorders of calcium metabolism. Patients with erythrodermic, exfoliative and pustular psoriasis.

Precautions

Not to be used on face, axillae or groin. Not to be applied to more than 30% of the body surface area. Monitor serum calcium levels; treatment should be temporarily discontinued if levels exceeded normal range. Prolonged usage or concurrent use with occlusive dressings may increase absorption of the drugs into the systemic circulation. Regular monitoring for evidence of hypothalamic-pituitary-adrenal axis suppression is recommended. Efficacy and safety have not been evaluated in patients with severe renal or hepatic impairment. Pregnancy and lactation.

Pregnancy-Lactation

Pregnancy The limited data on use in pregnant women are not sufficient to evaluate associated risk for major birth defects, miscarriages, or adverse maternal or fetal outcomes; observational studies suggest an increased risk of having low birth weight infants with the maternal use of potent or very potent topical corticosteroids; advise pregnant women that therapy may increase potential risk of having a low birth weight infant and to use product on smallest area of skin and for shortest duration possible; in animal reproduction studies Lactation There is no information regarding presence of topically administered calcipotriene and betamethasone dipropionate in human milk, effects on breastfed infant, or on milk production; not known whether topically administered calcipotriene or corticosteroids could result in sufficient systemic absorption to produce detectable quantities in human milk; developmental and health benefits of breastfeeding should be considered along with mother’s clinical need for therapy and any potential adverse effects on breastfed child from therapy or from underlying maternal condition; to minimize potential exposure to breastfed infant via breast milk, use drug on smallest area of skin and for shortest duration possible while breastfeeding; advise breastfeeding women not to apply drug directly to nipple and areola to avoid direct infant exposure

Interactions

Side Effects

Side effects of Betamethasone 0.05% + Calcipotriol 0.005% topical : Pruritus, rash, burning sensation of the skin, dry skin, erythema, rash, dermatitis, eczema, photosensitivity and hypersensitivity reactions. May aggravate psoriasis.

Mode of Action

Betamethasone dipropionate is a synthetic corticosteroid that has anti-inflammatory, antipruritic and vasoconstrictive properties. Calcipotriol is a vitamin D analogue. It may induce differentiation and suppress proliferation of keratinocytes.

Note

Dyvon Plus 50 mg + 5 mg/100 gm Topical Suspension generic name is Betamethasone 0.05% + Calcipotriol 0.005% topical. Dyvon Plus 50 mg + 5 mg/100 gm Topical Suspension is manufactured by Square Pharmaceuticals Ltd.Dyvon Plus is availble in all over Bangladesh. Mes BD drug index information on Dyvon Plus Topical Suspension is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Betamethasone 0.05% + Calcipotriol 0.005% topical :

Ointment

Dyvon Plus ^{.05 gm + .005 gm/100 gm}

Square Pharmaceuticals Ltd.

Ointment

Soria-D ^{.05 gm + .005 gm/100 gm}

Ziska Pharmaceuticals Ltd.

Ointment

Betol ^{.05 gm + .005 gm/100 gm}

Acme Laboratories Ltd.

Ointment

Planex Plus ^{.05 gm + .005 gm/100 gm}

Incepta Pharmaceuticals Ltd.

Cream

F-Gurd ^0.05%+1%

Ethical Drug Ltd.