Dostimid Tablet
Pyridostigmine
60mg
Unimed & Unihealth Manufacturers Ltd.
| Pack size | 14's pack |
|---|---|
| Unite Price | 22.00 BDT |
Indications
Dostimid Tablet is used for:
Reversal of neuromuscular blockade, Myasthenia gravis, Paralytic ileus, post-operative urinary retention
Adult Dose
Oral
Myasthenia gravis
Adult: 30-120 mg in divided doses, up to a total daily dose of 0.3-1.2 g.
Paralytic ileus and postoperative urinary retention
Adult: 60-240 mg daily.
Child Dose
Oral
Myasthenia gravis
Child: <6 yr Initially, 30 mg; 6-12 yr Initially, 60 mg. Doses are repeated throughout the day up to a usual total daily dose of 30-360 mg, w/ increments of 15-30 mg daily until a satisfactory response is obtained.
Paralytic ileus and postoperative urinary retention
Child: 15-60 mg daily.
Renal Dose
Renal impairment: Lower initial dose may be needed, titrate to desired effect.
Administration
Should be taken with food.
Contra Indications
Mechanical GI or urinary obstruction.
Precautions
Patient w/ bronchial asthma, COPD, bradycardia, cardiac arrhythmias, vagotonia, peptic ulcer, epilepsy or parkinsonism, hyperthyroidism. Renal impairment. Childn. Pregnancy and lactation. Monitoring Parameters Monitor cholinergic reaction particularly in IV admin.
Pregnancy-Lactation
Pregnancy Category: B
Lactation: Compatible
Interactions
May exacerbate night vision problems w/ anti-glaucoma drugs. Antagonises the effect of non-depolarising muscle relaxants (e.g. pancuronium, vecuronium). Prolongs the effect of depolarising muscle relaxants (e.g. suxamethonium).
Side Effects
Side effects of Pyridostigmine :
Nausea, vomiting, diarrhoea, increased peristalsis and bronchial secretions, miosis, excessive salivation and sweating, abdominal cramps, bradycardia, bronchospasm, skin rash, muscle spasm, fasciculation, muscle weakness.
Potentially Fatal: Resp paralysis, cardiac arrest, pulmonary oedema.
Mode of Action
Pyridostigmine bromide facilitates impulse transmission across the myoneural junction by inhibiting the destruction of acetylcholine by acetylcholinesterase. It also has direct cholinomimetic effect on skeletal muscles.
Note
Dostimid 60mg Tablet generic name is Pyridostigmine. Dostimid 60mg Tablet is manufactured by Unimed & Unihealth Manufacturers Ltd.Dostimid is availble in all over Bangladesh.
Mes BD drug index information on Dostimid Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.