Dextrobac Eye Drops

Dexamethasone 0.1% + Tobramycin 0.3% Eye prep

100 mg + 300 mg/100 ml

Incepta Pharmaceuticals Ltd.

Pack size	5 ml drop
Unite Price	150.00 BDT

Indications

Dextrobac Eye Drops is used for: Bacterial eye infections, Ocular inflammation, Pink eye

Adult Dose

Ophthalmic Ocular inflammation with suspected or confirmed bacterial infection Adult: As Eye Drops: 1-2 drops instilled into the conjunctival sac(s) 4-6 hrly. Dosage may be increased to every 2 hrly during the initial 24-48 hr, decrease frequency gradually as improvement seen. As Ointment: Apply about ½ inch of ointment into the conjunctival sac(s) up to 3-4 times daily.

Child Dose

Ophthalmic Ocular inflammation with suspected or confirmed bacterial infection <2 years Safety and efficacy not established >2 years As Eye Drops: 1-2 drops instilled into the conjunctival sac(s) 4-6 hrly. Dosage may be increased to every 2 hrly during the initial 24-48 hr, decrease frequency gradually as improvement seen. As Ointment: Apply about ½ inch of ointment into the conjunctival sac(s) up to 3-4 times daily.

Renal Dose

Administration

Contra Indications

Viral infections of corneal and conjunctiva (e.g. epithelial herpes simplex keratitis, vaccinia, varicella). Mycobacterial or fungal infection of the eye.

Precautions

Pregnancy and lactation. Avoid prolonged use, monitor intraocular pressure routinely. Safety and effectiveness in children <2 yr not established. Lactation: Excretion in milk unknown; use with caution

Pregnancy-Lactation

Pregnancy Category: C Lactation: Excretion in milk unknown; use with caution

Interactions

Antagonistic effect w/ neostigmine and pyridostigmine. May potentiate the effect of warfarin and phenindione.

Side Effects

Side effects of Dexamethasone 0.1% + Tobramycin 0.3% Eye prep : Hypersensitivity reactions, lid itching and swelling, conjunctival erythema, increase in intraocular pressure, glaucoma, optic nerve damage, posterior subcapsular cataract formation and delayed wound healing. Secondary infections especially after prolonged use.

Mode of Action

Tobramycin, an aminoglycoside antibiotic, has actions similar to that of gentamicin and is active against Staphylococci, Streptococci, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus mirabilis, Morganella morganii, most Proteus vulgaris strains, Haemophilus influenzae and H. aegyptius, Moraxella lacunata, Acinetobacter calcoaceticus and some Neisseria species. Dexamethasone, a synthetic fluorinated corticosteroid, has mainly glucocorticoid activity and suppresses inflammatory response.

Note

Dextrobac 100 mg + 300 mg/100 ml Eye Drops generic name is Dexamethasone 0.1% + Tobramycin 0.3% Eye prep. Dextrobac 100 mg + 300 mg/100 ml Eye Drops is manufactured by Incepta Pharmaceuticals Ltd.Dextrobac is availble in all over Bangladesh. Mes BD drug index information on Dextrobac Eye Drops is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Dexamethasone 0.1% + Tobramycin 0.3% Eye prep :

Eye Drops

Cinarex-D ^{100 mg + 300 mg/100 ml}

Beximco Pharmaceuticals Ltd.

Eye Ointment

Eytex ^{100 mg + 300 mg/100 gm}

Nipa Pharmaceuticals Ltd.

Eye Drops

Orbidex T ^{0.1% + 0.3%}

Popular Pharmaceuticals Ltd.

Eye Drops

T Dex ^{100 mg + 300 mg/100 ml}

Reman Drug Laboratories Ltd.

Eye Ointment

T Dex ^{100 mg + 300 mg/100 gm}

Reman Drug Laboratories Ltd.