Indications
Dex I Tablet is used for:
Osteoarthritis, Pain, Fever, Pericarditis, Dysmenorrhea, Rheumatic disorders, Patent ductus arteriosus
Adult Dose
Oral
Pain and inflammation associated with musculoskeletal and joint disorders ; Dysmenorrhoea
Adult: 600-900 mg daily in 2-3 divided doses. May increase to 1200 mg daily for patients with acute conditions or exacerbations.
Max Dosage: 400 mg/dose and 1200 mg/day.
Hepatic impairment: Dose reduction is recommended.
Child Dose
Renal Dose
Renal impairment: Dose reduction is recommended.
Administration
Contra Indications
Hypersensitivity to aspirin or NSAIDs; active or suspected GI ulcer or history of recurrent GI ulcer; GI bleeding or other active bleedings or bleeding disorders; active Crohn's disease or ulcerative colitis; haemorrhagic diasthesis and other coagulation disorders, or patients receiving anticoagulant therapy; severe heart failure, renal or hepatic impairment; child <18 yrs; pregnancy (third trimester).
Precautions
History of bronchial asthma; renal or hepatic disorders; bleeding disorders; CV disease; elderly; lactation.
Pregnancy-Lactation
Interactions
Avoid concomitant use with anticoagulants, other NSAIDs and salicylates. Increases risk of methotrexate and lithium toxicity.
Side Effects
Side effects of Dexibuprofen :
GI bleeding, heartburn, epigastric pain; dyspepsia, peptic ulcer; nausea, vomiting, diarrhoea; jaundice, hepatitis; rash; thrombocytopaenia; visual disturbances; tinnitus; depression; fatigue, headache, dizziness, vertigo.
Mode of Action
Dexibuprofen is a NSAID. It acts by inhibition of cyclo-oxygenase, which is involved in prostaglandin synthesis.
Note
Dex I 300mg Tablet generic name is Dexibuprofen. Dex I 300mg Tablet is manufactured by Edruc Ltd.Dex I is availble in all over Bangladesh.
Mes BD drug index information on Dex I Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.