Danxit Tablet
Flupenthixol + Melitracen
500mcg + 10mg
Astra Biopharmaceuticals Ltd.
| Pack size | |
|---|---|
| Unite Price | 4.00 BDT |
Indications
Danxit Tablet is used for:
Depression, Anxiety, Apathy, Dysphoria
Adult Dose
Adults: Usually 2 tablets daily; morning and noon. In severe cases the morning dose may be increased to 2 tablets.
Elderly: 1 tablet in the morning.
Maintenance dose: Usually 1 tablet in the morning. In cases of insomnia or severe restlessness additional treatment with a sedative in the acute phase is recommended.
Child Dose
Renal Dose
Administration
Contra Indications
The immediate recovery phase after myocardial infarction, Defects in bundle-branch conduction, Untreated narrow angle glaucoma, Acute alcohol, barbiturate and opiate intoxications, Flupentixol-Melitracen should not be given to patients who have received a MAO-inhibitor within two weeks. Not recommended for excitable or overactive patients since its activating effect may lead to exaggeration of these characteristics.
Precautions
If previously the patient has been treated with tranquilizers with sedative effect these should be withdrawn gradually.
Pregnancy-Lactation
Interactions
May potentiate the adverse effects of drugs with antimuscarinic effects e.g. TCAs. Reduced efficacy of levodopa. Increases adverse extrapyramidal symptoms with dopamine antagonists (metoclopramide and prochlorperazine).
Potentially Fatal: Potentiates CNS effects of alcohol, general anaesthetics, hypnotics, anxiolytics and opioids. Blocks antihypertensive effect of guanethidine.
Additive toxicity with antimuscarinics, CNS depressants. Response to TCA may be accelerated with thyroid hormones; pressor effects of sympathomimetics may be enhanced; risk of serotonin syndrome when taken with other antidepressants. Antidiabetic dosage may need to be adjusted.
Side Effects
Side effects of Flupenthixol + Melitracen :
In the recommended doses side effects are rare. These could be transient restlessness and insomnia.
Mode of Action
Flupentixol is a thioxanthene antipsychotic that inhibits dopamine-mediated effects by blocking postsynaptic dopamine receptors in the CNS.
Melitracen is a TCA with anxiolytic properties.
Note
Danxit 500mcg + 10mg Tablet generic name is Flupenthixol + Melitracen. Danxit 500mcg + 10mg Tablet is manufactured by Astra Biopharmaceuticals Ltd.Danxit is availble in all over Bangladesh.
Mes BD drug index information on Danxit Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.