Coolgut Chewable Tablet

Hyoscine Hydro Bromide
150mcg
Incepta Pharmaceuticals Ltd.
Pack size 30's Pack
Unite Price 5.00 BDT

Indications

Coolgut Chewable Tablet is used for: Motion sickness

Adult Dose

Adult: Motion sickness As hydrobromide: 300 mcg 30 mins before journey, then 300 mcg 6 hrly if needed. Max: 3 doses in 24 hr.

Child Dose

Children over 12 years: Motion sickness As hydrobromide: 300 mcg 30 mins before journey, then 300 mcg 6 hrly if needed. Max: 3 doses in 24 hr. Children 4-12 years: 1 tablet 30 mins before journey. Maximum 2 tablet in 24 hours. Chidren 3-4 years: 1/2 tab 30 mins before journey. Maximum 1 tablet in 24 hours.

Renal Dose

Administration

Contra Indications

Narrow-angle glaucoma, acute haemorrhage, paralytic ileus, tachycardia due to cardiac insufficiency, myasthenia gravis.

Precautions

Hepatic/renal disease, pyloric stenosis, urinary retention, prostatic hyperplasia, psychosis, seizure disorders, ulcerative colitis, coronary artery disease, tachyarrhythmias, heart failure, hypertension. Elderly, children, pregnancy, lactation

Pregnancy-Lactation

Interactions

Additive sedative effects with alcohol or other CNS depressants. Reduced effects with acetylcholinesterase inhibitors (donepezil, galantamine, rivastigmine, tacrine). Potentially Fatal: Effect potentiated by other anticholinergic drugs and TCAs.

Side Effects

Side effects of Hyoscine Hydro Bromide : Flushing, postural hypotension, tachycardia, fibrillation. Rarely psychotic reactions. Dizziness, drowsiness, fatigue, headache, memory loss. Dry skin, erythema, increased sensitivity to light, rash. Bloatedness, constipation, dry throat, dysphagia, nausea, vomiting, xerostomia. Dysuria, urinary retention. Tremor, weakness. Impaired accommodation, blurred vision, cycloplegia, dryness, narrow-angle glaucoma, increased intraocular pain, itching, photophobia, pupil dilation. Dry nose. Decreased diaphoresis, heat intolerance. Ophthalmic: Somnolence, dermatitis, oedema, exudate, follicular conjunctivitis, increased IOP, local irritation, photophobia, vascular and respiratory congestion. Potentially Fatal: CNS depression, coma, circulatory and respiratory failure.

Mode of Action

Hyoscine competitively blocks muscarinic receptors and has central and peripheral actions. It relaxes smooth muscle and reduces gastric and intestinal motility.

Note

Coolgut 150mcg Chewable Tablet generic name is Hyoscine Hydro Bromide. Coolgut 150mcg Chewable Tablet is manufactured by Incepta Pharmaceuticals Ltd.Coolgut is availble in all over Bangladesh. Mes BD drug index information on Coolgut Chewable Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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