Combiderm Cream
Betamethasone + Clotrimazole + Gentamicin Topical
0.05% + 1% + 0.1%
Popular Pharmaceuticals Ltd.
| Pack size | 15 g |
|---|---|
| Unite Price | 75.00 BDT |
Indications
Combiderm Cream is used for:
Acute & chronic eczema, contact dermatitis, atopic dermatitis, seborrheic dermatitis, chronic simple lichen, intertrigo, exfoliative dermatitis, papular urticaria, psoriasis, pruritus vulvae, pruritus ani, dermatitis solaris; skin mycosis (athlete's foot, trichophytia), tinea versicolor; insect bite, skin disease by secondary bacterial infection.
Adult Dose
Apply thin film to affected skin areas 2 times daily. Limit treatment to less than 45g per week.
Duration of therapy varies depending upon the extent and location of disease and patient response. However, if clinical improvement is not achieved by 3-4 weeks, diagnosis should be reviewed.
Child Dose
Renal Dose
Administration
Contra Indications
Hypersensitivity to any of the ingredients.
Tuberculosis and most viral lesion of the skin, particularly herpes simplex, vaccinia and varicella.
Precautions
Similar effect to systemic steroid therapy may occur in large amount use or long-term therapy by occlusive dressing technique (ODT). Local adverse effect eg, skin atrophy, facial erythema may occur. Manifestations hypersensitivity eg, itching, flare, vesicle and urticaria may occur. Discontinue using if these reactions occur. Do not use in overdosage or ODT in prolonged period of therapy.
Do not use in the eyes.
Discontinue use in case of no improvements or condition worsens; as soon as possible improvements happen.
Use in pregnancy & lactation.
Pregnancy-Lactation
Interactions
Side Effects
Side effects of Betamethasone + Clotrimazole + Gentamicin Topical :
Continuous application without interruption may result in local atrophy of the skin, striae and superficial vascular dilation. Rarely, patients may experience local mild burning or irritation.
Topical use of gentamicin may cause ototoxicity and/or nephrotoxicity when applied to large burned areas or for extended periods of time, especially in patients with renal insufficiency or when administered concurrently with other drugs that are potentially ototoxic or nephrotoxic.
Mode of Action
Betamethasone dipropionate is a synthetic fluorinated corticosteroid. It is active topically and produces a rapid and sustained response in those inflammatory dermatoses that are normally responsive to topical corticosteroid therapy.
Gentamicin sulfate is a bactericidal antibiotic active against a wide variety of pathogenic gram-negative and gram-positive bacteria.
Clotrimazole is a broad-spectrum antifungal. It also exhibit activity against Trichomonas, Staphylococci, Streptococci and Bacteroides.
At a combination of 3 agents with distinct pharmacological effects, Gentriderm offers superior anti-inflammatory, antipruritic, bactericidal and fungicidal action for treatment of inflammatory and allergic dermatological conditions threatened or complicated by bacterial and/or common fungal infections.
Note
Combiderm 0.05% + 1% + 0.1% Cream generic name is Betamethasone + Clotrimazole + Gentamicin Topical. Combiderm 0.05% + 1% + 0.1% Cream is manufactured by Popular Pharmaceuticals Ltd.Combiderm is availble in all over Bangladesh.
Mes BD drug index information on Combiderm Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.