Clindacin Vaginal Cream

Clindamycin 2% Vaginal prep
600 mg/4 ml
Incepta Pharmaceuticals Ltd.
Pack size 20 gm
Unite Price 70.00 BDT

Indications

Clindacin Vaginal Cream is used for: Bacterial vaginosis

Adult Dose

Bacterial Vaginosis Vaginal cream: 1 full applicator inserted (approximately 5 gram) intravaginally at bedtime for 3 days in nonpregnant patients and for 7 days in pregnant patients

Child Dose

<12 years old Safety and efficacy not established

Renal Dose

Administration

Contra Indications

Hypersensitivity.Clindamycin cream is also contraindicated in individuals with a history of regional enteritis, ulcerative colitis, or a history of \"antibiotic-associated\" colitis.

Precautions

The patient should be instructed not to engage in vaginal intercourse, or use other vaginal products during treatment with this product. This cream contains mineral oil that may weaken latex or rubber products such as condoms or vaginal contraceptive diaphragms. Therefore, use of such products within 72 hours following treatment with Clindacin cream is not recommended. Lactation: Excretion in milk unknown; use with caution

Pregnancy-Lactation

Interactions

May enhance the action of neuromuscular blocking agents (e.g. atracurium). May antagonise the effects of parasympathomimetics. May competitively inhibit the effects of macrolides, ketolides, streptogramins, linezolid and chloramphenicol. Increased coagulation tests (prothrombin time/INR) and/or bleeding w/ vit K antagonists (e.g. warfarin, acenocoumarol, fluindione).

Side Effects

Side effects of Clindamycin 2% Vaginal prep : Genital tract: vaginitis, vulvo-vaginal irritation Central nervous system: dizziness, headache, vertigo. Gastro-intestinal: heartburn, nausea, vomiting, diarrhea, constipation, abdominal pain. Dermatological: rash, exanthema. Hypersensitivity: urticaria.

Mode of Action

Clindamycin inhibits protein synthesis by reversibly binding to the 50S subunit of the ribosomal thus blocking the transpeptidation or translocation reactions of susceptible organisms resulting to stunted cell growth.

Note

Clindacin 600 mg/4 ml Vaginal Cream generic name is Clindamycin 2% Vaginal prep. Clindacin 600 mg/4 ml Vaginal Cream is manufactured by Incepta Pharmaceuticals Ltd.Clindacin is availble in all over Bangladesh. Mes BD drug index information on Clindacin Vaginal Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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