Indications
Citin Syrup is used for:
Allergic rhinitis, Hay fever, Allergies, Urticaria
Adult Dose
Oral
Allergic conditions
Adult: 10 mg once daily or 5 mg bid.
Elderly: Initially, 5 mg once daily.
Hepatic impairment: Initially, 5 mg once daily.
Syrup:
Adults: 2 teaspoon once daily or 1 teaspoon twice daily.
Child Dose
Oral
Allergic conditions
Child: 6-23 mth 2.5 mg once daily increased to max of 2.5 mg bid in childn >12 mth; 2-5 yr 5 mg once daily or in 2 divided doses; >6 yr 10 mg once daily or in 2 divided doses.
Syrup:
Children over 6 years: 2 teaspoon once daily or 1 teaspoon twice daily.
Children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoon twice daily.
<2 years: Safety and efficacy not established
Renal Dose
Renal impairment
GFR >50 mL/min: Dose adjustment not necessary
GFR< 50 mL/min: 5 mg PO qDay
Peritoneal dialysis: 5 mg PO qDay
Intermittent hemodialysis: 5 mg PO qDay; may also administer 3 times weekly
Administration
May be taken with or without food.
Contra Indications
Hypersensitivity; lactation.
Precautions
Hepatic or renal impairment; elderly; tasks requiring mental alertness eg, driving or operating heavy machinery; pregnancy.
Lactation: Excreted in breast milk; use not recommended
Pregnancy-Lactation
Pregnancy
There are no adequate and well-controlled studies in pregnant women
Lactation
Cetirizine has been reported to be present in human breast milk
In mice and beagle dogs, studies indicated that cetirizine was excreted in milk
When a drug is present in animal milk, it is likely it will be present in human milk
Interactions
Additive CNS depression when administered concomitantly w/ other CNS depressants (e.g. sedatives, tranquilisers).
Side Effects
Side effects of Cetirizine :
>10%
Somnolence (2-14%), Headache (11-14%)
1-10%
Fatigue (5.9%), Dry mouth (5%), Dizziness (2%), Diarrhea (2-3%), Malaise (4%), Bronchospasm (2-3%), Vomiting (2-3%), Epistaxis (2-4%)
<1%
Stomach pain, Drowsiness, Angioedema, Fussiness, Hallucinations, Hypotension, Tremor, Tongue discoloration
Mode of Action
Cetirizine is a potent and highly selective antagonist of the peripheral histamine H1-receptor on effector cells in the GI tract, blood vessels and resp tract.
Note
Citin 5mg/5ml Syrup generic name is Cetirizine. Citin 5mg/5ml Syrup is manufactured by Opsonin Pharma LimitedCitin is availble in all over Bangladesh.
Mes BD drug index information on Citin Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.