Cino Plus Suppository
Cinchocaine Hydrochloride 0.5% + Esculin 1% + Hydrocortisone + Neomycin Sulphate (Rectal prep)
5 mg + 10 mg + 5 mg + 10
Acme Laboratories Ltd.
| Pack size | 10's pack |
|---|---|
| Unite Price | 67.70 BDT |
Indications
Cino Plus Suppository is used for:
Pruritus ani, Haemorrhoids, Anal fissure, Proctitis
Adult Dose
Adult: Apply onto the affected area in the morning and evening and after each stool.
As suppository: Insert 1 suppository in the morning and evening and after each stool.
Child Dose
Renal Dose
Administration
Contra Indications
Complete heart block; pyogenic infection at or near the skin. Application to inflamed or infected tissues or to damaged skin mucosa; instillation into the middle ear.
Precautions
Elderly; debilitated patients; child; epilepsy; impaired cardiac conduction or respiratory function; shock; hepatic impairment; myasthenia gravis. Do not to rub or touch the eye while anaesthesia persists. Avoid application for prolonged periods and to extensive areas. Pregnancy, lactation.
Pregnancy-Lactation
Interactions
Side Effects
Side effects of Cinchocaine Hydrochloride 0.5% + Esculin 1% + Hydrocortisone + Neomycin Sulphate (Rectal prep) :
Restlessness; excitement; nervousness; paraesthesias; dizziness; tinnitus; blurred vision; nausea; vomiting; muscle twitching; tremors; convulsions; hypotension; bradycardia; arrhythmias; cardiac arrest.
Mode of Action
Cinchocaine prevents or diminishes nerve impulse conduction near to the site of admin. It also has membrane-stabilising effect owing to decrease of permeability of the nerve cell to sodium ions.
Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It may also be used as replacement therapy in adrenocortical insufficiency.
Neomycin is an aminoglycoside antibiotic. It binds to 30S ribosomal subunits of bacterial ribosome thus inhibiting protein synthesis and generating errors in genetic code transcription causing cell death. It acts against many gram-negative aerobes and some gram-positive aerobes. It lacks activity against fungi, viruses and most anaerobic bacteria.
Esculin improves skin vasculature and is effective in the management of cellulitis.
Note
Cino Plus 5 mg + 10 mg + 5 mg + 10 Suppository generic name is Cinchocaine Hydrochloride 0.5% + Esculin 1% + Hydrocortisone + Neomycin Sulphate (Rectal prep). Cino Plus 5 mg + 10 mg + 5 mg + 10 Suppository is manufactured by Acme Laboratories Ltd.Cino Plus is availble in all over Bangladesh.
Mes BD drug index information on Cino Plus Suppository is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.