Cinagen Eye Drops
Moxifloxacin 0.5% Eye prep
0.5%
Navana Pharmaceuticals Ltd.
| Pack size | 5ml bot |
|---|---|
| Unite Price | 140.00 BDT |
Indications
Cinagen Eye Drops is used for:
Bacterial Conjunctivitis. This drug is indicated to increase tear production in patients whose tear production is suppressed due to ocular inflammation associated with dry eye syndrome (keratoconjunctivitis sicca).
Adult Dose
Ophthalmic
Bacterial conjunctivitis
Adult: As 0.5% soln: Instill 1 drop into the affected eye(s) bid-tid for 7 days.
It can be used concomitantly with artificial tears, allowing a 15 minute interval between products.
Child Dose
Ophthalmic
Bacterial conjunctivitis
Child: >1 yr: Instill 1 drop into the affected eye(s) tid for 7 days.
Renal Dose
Administration
Contra Indications
Patients with a history of hypersensitivity to Moxifloxacin, to other Quinolones or to any of the components in this medication
Precautions
As with other anti-infectives, prolonged use may result in overgrowth of non-susceptible organisms, including fungi. If superinfection occurs, discontinue use and institute alternative therapy. To prevent contamination do not touch the tip of the dropper to eye, eyelid or any surface of of the affected eye. Keep the bottle tightly closed after use.
Lactation: Unknown whether drug is excreted in breast milk; use with caution
Pregnancy-Lactation
Pregnancy
There are no available human data establishing a drug associated risk; however, when moxifloxacin was administered to rats during pregnancy and throughout lactation at doses associated with maternal toxicity, decreased neonatal body weights, increased incidence of skeletal variations (rib and vertebra combined), and increased fetal loss were observed
Advise pregnant women of potential risk to fetus
Lactation
Not known if moxifloxacin is present in human milk
Based on animal studies in rats, moxifloxacin may be excreted in human milk
Developmental and health benefits of breastfeeding should be considered along with mother’s clinical need for therapy and any potential adverse effects on the breastfed child from drug or from the underlying maternal condition
Interactions
Additive effect on QT interval prolongation w/ other drugs that prolong QT interval (e.g. erythromycin, TCAs, antipsychotic agents). Decreased absorption and bioavailability w/ Al- or Mg-containing antacids, or Fe or Zn preparations. Concomitant use of corticosteroids increases the risk of severe tendon disorders esp in elderly (>60 yr). Decreased absorption w/ sucralfate or didanosine.
Potentially Fatal: Concurrent use of class Ia (e.g. quinidine, procainamide) or III (e.g. amiodarone, sotalol) antiarrhythmic drugs or w/ other drugs that prolong QT interval (e.g. erythromycin, TCAs, antipsychotic agents) may cause additive effect on QT interval prolongation.
Side Effects
Side effects of Moxifloxacin 0.5% Eye prep :
1-10%
Conjunctivitis, Dry eye, Fever, Increased cough, Infection, Ocular discomfort, Ocular hyperemia, Ocular pain, Ocular pruritus, Otitis media.Pharyngitis, Rash, Rhinitis, Subconjunctival hemorrhage.Tearing
Mode of Action
Moxifloxacin inhibits the topoisomerase II (DNA gyrase) and topoisomerase IV required for bacterial DNA replication, transcription, repair and recombination.
Note
Cinagen 0.5% Eye Drops generic name is Moxifloxacin 0.5% Eye prep. Cinagen 0.5% Eye Drops is manufactured by Navana Pharmaceuticals Ltd.Cinagen is availble in all over Bangladesh.
Mes BD drug index information on Cinagen Eye Drops is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.