Cardobis M Tablet
Bisoprolol + Amlodipine
2.5mg + 5mg
Eskayef Pharmaceuticals Ltd.
Pack size | 30's pack |
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Unite Price | 6.00 BDT |
Indications
Cardobis M Tablet is used for:
Treatment of mild to moderate hypertension
Adult Dose
Oral
Adult
1 tablet once daily
Child Dose
Renal Dose
Administration
Contra Indications
Cardiogenic shock, overt cardiac failure, second or third degree AV block, and marked sinus bradycardia and known sensitivity to amlodipine/bisoprolol.
Precautions
Bisoprolol: Overt congestive cardiac failure, abrupt cessation of therapy, peripheral vascular disease, bronchospastic disease, anesthesia and major surgery, diabetes and hypoglycaemia and thyrotoxicosis.
Amlodipine: Severe aortic stenosis, congestive heart failure and hepatic failure
This medicine is not recommended for use in breastfeeding women unless absolutely necessary.
Pregnancy-Lactation
Interactions
Side Effects
Side effects of Bisoprolol + Amlodipine :
Edema, headache, increase heart rate, sneezing, fatigue, leg cramps, dry mouth. Other adverse events reported were gastric irritation, angina, asthma, cold extremities, cough, decrease in libido, dizziness, facial flushing, postural hypotension, skin rash, sleep disturbance and vertigo.
Mode of Action
Bisoprolol selectively and competitively blocks β1-receptors but has little or no effect on β2-receptors except at high doses.
Amlodipine relaxes peripheral and coronary vascular smooth muscle. It produces coronary vasodilation by inhibiting the entry of Ca ions into the slow channels or select voltage-sensitive channels of the vascular smooth muscle and myocardium during depolarisation. It also increases myocardial oxygen delivery in patients w/ vasospastic angina.
Note
Cardobis M 2.5mg + 5mg Tablet generic name is Bisoprolol + Amlodipine. Cardobis M 2.5mg + 5mg Tablet is manufactured by Eskayef Pharmaceuticals Ltd.Cardobis M is availble in all over Bangladesh.
Mes BD drug index information on Cardobis M Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.