Carbestop Injection
Carboprost
250 mcg/ml
Incepta Pharmaceuticals Ltd.
| Pack size | 1's Pack |
|---|---|
| Unite Price | 200.00 BDT |
Indications
Carbestop Injection is used for:
Pregnancy termination in the 2nd trimester (Abortion), Postpartum Uterine Bleeding
Adult Dose
Intramuscular
Pregnancy termination in the 2nd trimester/Abortion
Adult: Initially, 250 mcg. Alternatively, initiate w/ test dose of 100 mcg. May be repeated at 1.5- to 3.5-hr intervals depending on uterine response. May be increased to 500 mcg if uterine contractility is inadequate.
Max: 12 mg. Max duration: 2 days.
Intramuscular
Postpartum haemorrhage
Adult: Initially, 250 mcg by deep inj. May be repeated every 15-90-min. Max: 2 mg.
Child Dose
Renal Dose
Administration
Contra Indications
Acute pelvic inflammatory disease; active cardiac, pulmonary, renal or hepatic disease.
Precautions
History of glaucoma or raised IOP
Asthma, hypertension/hypotension, cardiovascular disease
Transient fever observed with treatment possibly as a result of carboprost's effect on hypothalamic thermoregulation
Caution in patients with anemia, jaundice, renal impairment, hepatic impairment diabetes or epilepsy
To decrease GI side effects pretreatment or concomitant use with antiemetic and antidiarrheal agents recommended
Not for IV
Rare cases of cardiovascular collapse reported with prostaglandins
Lactation: Excretion in milk unknown
Pregnancy-Lactation
Pregnancy Category: C
Lactation: Excretion in milk unknown
Interactions
May potentiate effect of other oxytocics.
Side Effects
Side effects of Carboprost :
Nausea (1/3 patients), Vomiting (~2/3 patients), Diarrhea (~2/3 patients)
Nervousness, Epistaxis, Sleep disorder, Hyperthermia, Flushing, Asthma, Wheezing, Coughing, Chest pain, Hypertension, Syncope, Palpation, Tachycardia, Chest tightness, Anxiety, Chills/shivering, Dizziness, Drowsiness, Dystonia, Faintness, Headache, Lethargy, Lightheadedness, Vertigo, Rash, Breast tenderness, Dysmenorrhea-like pain, Hot flashes, Dry throat.Taste alterations, Uterine bleeding (excessive)
Local: injection site pain
Backache, Leg cramps, Muscular pain, Parethesia, Blurred vision, Eye pain, Eyelid twitching, Tinnitus, Bronchospasm, Dyspnea, Hiccups
Mode of Action
Carboprost, a synthetic analogue of naturally occurring prostaglandin F2α, stimulates uterine contractility, resulting in expulsion of the products of conception. It is also used to induce abortion between 13-20 wk of pregnancy. It produces myometrial contractions responsible for placental haemostasis.
Note
Carbestop 250 mcg/ml Injection generic name is Carboprost. Carbestop 250 mcg/ml Injection is manufactured by Incepta Pharmaceuticals Ltd.Carbestop is availble in all over Bangladesh.
Mes BD drug index information on Carbestop Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.