Calcium Ambee Injection
Calcium Gluconate
500mg/5ml
Ambee Pharmaceuticals Ltd.
| Pack size | 5 amps x 5's pack |
|---|---|
| Unite Price | 6.22 BDT |
Indications
Calcium Ambee Injection is used for:
Postmenopausal osteoporosis, Osteoporosis, Hypoparathyroidism, Latent tetany, Rickets, Osteomalacia, Hyperkalemia, Hypocalcemia, Magnesium sulfate overdose
Adult Dose
Hypocalcemia
Treatment of conditions arising from calcium deficiency (eg, hypocalcemic tetany, hypoparathyroidism)
Mild (ionized calcium 1-1.2 mmol/L)
Management of non-life-threatening symptoms
IV: 1-2 g over 2 hours
Severe (ionized calcium <1 mmol/L)
Without seizure or tetany: 0.5 mg/kg/hr IV; may be increased to 2 mg/kg/hr; not to exceed 3-4 g IV over 4 hours
Hypocalcemic tetany: 100-300 mg elemental calcium (~3 g calcium gluconate) IV over 5-10 minutes, followed by continuous IV infusion at 0.5 mg/kg/hr (may be increased to 2 mg/kg/hr)
Monitor serum calcium q4-6hr to maintain serum calcium levels
Child Dose
Hypocalcemia
Treatment of conditions arising from calcium deficiency (eg, hypocalcemic tetany, hypoparathyroidism)
Severe
Neonates: 200-800 mg/kg/day IV by continuous infusion or divided q6hr as intermittent infusions
Infants/children: 200-500 mg/kg/day IV by continuous infusion or divided q6hr as intermittent infusions
Hypocalcemic tetany
100-200 mg/kg IV over 10 minutes; may be repeated after 6 hours, or initiate continuous infusion not to exceed 500 mg/kg/day
Renal Dose
Administration
Contra Indications
Patients with calcium renal calculi or history of renal calculi. Conditions associated with hypercalcaemia and hypercalciuria.
Precautions
Impaired renal function; cardiac disease; hypercalcaemia-associated diseases, e.g. sarcoidosis; other malignancies. Pregnancy.
Lactation: Calcium enters human milk; use with caution
Pregnancy-Lactation
Pregnancy category: C
Lactation: Calcium enters human milk; use with caution
Interactions
Calcium Gluconate: Co-admin of high calcium doses with thiazide diuretics may result in milk-alkali syndrome and hypercalcaemia. May potentiate digoxin toxicity. Decreases effects of calcium-channel blockers. Enhanced absorption with calcitriol (a vitamin D metabolite).
Side Effects
Side effects of Calcium Gluconate :
Bradycardia, Hypotension, Headache, Constipation, Diarrhea, Flatulence, Nausea, Vomiting, Hypomagnesemia, Hypophosphatemia, Extravasation necrosis
Hypercalcaemia characterised by anorexia, nausea, vomiting, constipation, abdominal pain, muscle weakness, mental disturbances, polydipsia, polyuria, nephrocalcinosis, renal calculi; chalky taste, hot flushes and peripheral vasodilation.
Potentially Fatal: Cardiac arrhythmias and coma.
Mode of Action
Calcium gluconate/lactate is used to prevent or treat negative calcium balance. It also helps facilitate nerve and muscle performance as well as normal cardiac function. Bone mineral component; cofoactor in enzymatic reactions, essential for neurotransmission, muscle contraction, and many signal transduction pathways.
Note
Calcium Ambee 500mg/5ml Injection generic name is Calcium Gluconate. Calcium Ambee 500mg/5ml Injection is manufactured by Ambee Pharmaceuticals Ltd.Calcium Ambee is availble in all over Bangladesh.
Mes BD drug index information on Calcium Ambee Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.