Budicort Nasal Spray
Budesonide 0.1% Nasal spray
100mcg
Incepta Pharmaceuticals Ltd.
| Pack size | 120mtered dose |
|---|---|
| Unite Price | 250.00 BDT |
Indications
Budicort Nasal Spray is used for:
Hay fever, nasal polyposis, seasonal and perennial allergic rhinitis, vasomotor rhinitis
Adult Dose
Nasal
Nasal polyps
Adult: As metered-dose spray (64 mcg or 100 mcg/dose): 1 spray into each nostril bid up to 3 mth; alternatively, 2 sprays into each nostril once daily for preparations containing 64 mcg/dose.
Allergic rhinitis
Adult: As metered-dose spray (64 mcg or 100 mcg/dose): Initially, 2 sprays into each nostril daily or 1 spray into each nostril bid, reduce to 1 spray into each nostril daily until symptoms are controlled.
Child Dose
Nasal
Nasal polyps
Child: >6 yr: As metered-dose spray (100 mcg/dose): 1 spray into each nostril bid up to 3 mth.
Nasal
Allergic rhinitis
Child: >6 yr: As metered-dose spray (100 mcg/dose): Initially, 2 sprays into each nostril daily or 1 spray into each nostril bid, reduce to 1 spray into each nostril daily until symptoms are controlled.
<6 years: Safety and efficacy not established
Renal Dose
Administration
Contra Indications
Hypersensitivity to any of the ingredients of this preparation.
Precautions
Budesonide nasal spray should be used with caution in patients with active or quiescent tuberculous infection, untreated fungal, bacterial, or systemic viral infections, or ocular herpes simplex infection. Patients with recent nasal septal ulcers, nasal surgery, or nasal trauma should not use a nasal corticosteroid.
Lactation: Distributed in breast milk; estimated total daily oral dose of budesonide available in breast milk to infant is ~0.3-1% of dose inhaled by mother
Pregnancy-Lactation
Pregnancy
Adverse events (eg, hypoadrenalism) observed with systemic corticosteroids in animal reproduction studies
Increased risk of abnormalities has not been demonstrated in pregnant women using intranasal budesonide
Clinical considerations: Intranasal corticosteroids are recommended for allergic rhinitis during pregnancy
Lactation
Excreted in breast milk after oral inhalation (~0.3-1% of the maternal dose)
Plasma budesonide levels obtained from infants after breast-feeding were below the limit of quantification
Interactions
The main route of metabolism of corticosteroids, including budesonide, is via cytochrome P450 (CYP) isoenzyme 3A4 (CYP3A4). After oral administration of ketoconazole, a strong inhibitor of CYP3A4, the mean plasma concentration of orally administered budesonide increased. Concomitant administration of CYP3A4 may inhibit the metabolism of, and increase the systemic exposure to, budesonide. Caution should be exercised when considering the co-administration of Budesonide Nasal Spray with long-term ketoconazole and other known strong CYP3A4 inhibitors (e.g., ritonavir, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, saquinavir, telithromycin).
Side Effects
Side effects of Budesonide 0.1% Nasal spray :
1-10%
Epistaxis (8%), Pharyngitis (4%), Bronchospasm (2%), Cough (2%), Nasal irritation (2%)
Mode of Action
Budesonide is a corticosteroid that has mainly glucocorticoid activity. It prevents and controls inflammation by controlling the rate of protein syntheis, decreasing the migration of polymorphonuclear leucocytes/fibroblasts and reversing capillary permeability.
Note
Budicort 100mcg Nasal Spray generic name is Budesonide 0.1% Nasal spray. Budicort 100mcg Nasal Spray is manufactured by Incepta Pharmaceuticals Ltd.Budicort is availble in all over Bangladesh.
Mes BD drug index information on Budicort Nasal Spray is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.