Biomo Lipon Injection
Alpha Lipoic Acid
600mg
ZAS Corporation
| Pack size | 5 amp packs |
|---|---|
| Unite Price | 820.00 BDT |
Indications
Biomo Lipon Injection is used for:
Diabetic neuropathy
Adult Dose
Infusion/Intravenous Injection
A typical treatment course for chronic pain is two to three IV infusions per week for three to four weeks, followed by maintenance infusions once every few months.
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Diabetes mellitus: Alpha lipoic acid may decrease blood glucose concentrations; patients with diabetes mellitus should use ALA with caution and monitor their blood glucose concentrations.
Pregnancy-Lactation
Evidence supporting the use of ALA in pregnancy and lactation is lacking. Women who are pregnant or breast-feeding their infants should avoid its use until information regarding safety and efficacy are available.
Interactions
Antidiabetic agents: Alpha lipoic acid has been shown to increase glucose utilization and decrease insulin resistance. Patients receiving antidiabetic agents in combination with ALA may be at increased risk for hypoglycemia; dosage adjustments of antidiabetic agents may be necessary. Furthermore, patients should be instructed to monitor their blood glucose concentrations while taking ALA. In one study, some patients with type 2 diabetes mellitus receiving both ALA and sulfonylureas required a dose reduction in the sulfonylurea due to mild symptoms of hypoglycemia.
Patients receiving other drugs that may decrease blood glucose concentrations or insulin resistance may enhance the beneficial effects of ALA, possibly causing hypoglycemia. Such drugs include ACE inhibitors, androgens, bortezomib, chromium, disopyramide, fibric acid derivatives, garlic, Allium sativum, green tea, guanethidine, horse chestnut, Aesculus hippocastanum, MAOIs, octreotide, and orlistat. Patients with diabetes taking ALA plus any of these other drugs should be advised to monitor their blood glucose concentrations.
Side Effects
Side effects of Alpha Lipoic Acid :
Alpha lipoic acid appears to be well-tolerated. In clinical trials of patients with diabetes, a few patients reported symptoms consistent with mild hypoglycemia. In addition, allergic skin conditions have been reported in patients taking oral ALA. In a study in patients with peripheral neuropathy, a dose-dependent increase in the incidence of nausea, vomiting and vertigo was reported with the highest incidence in those patients taking 1200 mg and 1800 mg/day PO of ALA.
Mode of Action
Alpha lipoic acid (ALA, thioctic acid) is an endogenous, potent antioxidant. Endogenous alpha lipoic acid is available as both an R- and S- enantiomer; the R-enantiomer is the biologically active component.
Evidence indicates that oxidative stress and lipid peroxidation are major causes of neuropathic pain and dysfunction. Because of its antioxidant properties, ALA has been shown to improve the symptoms of neuropathy in patients with diabetes. ALA protects against nerve oxidative damage, resulting in a beneficial effect on both the peripheral and central nervous system and also resulting in a positive influence on nerve conduction and nerve blood flow.
Note
Biomo Lipon 600mg Injection generic name is Alpha Lipoic Acid. Biomo Lipon 600mg Injection is manufactured by ZAS CorporationBiomo Lipon is availble in all over Bangladesh.
Mes BD drug index information on Biomo Lipon Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.