Benoxiclin Gel
Clindamycin + Benzoyl Peroxide
5gm + 1gm/100gm
Unimed & Unihealth Manufacturers Ltd.
| Pack size | 20gm |
|---|---|
| Unite Price | 350.00 BDT |
Indications
Benoxiclin Gel is used for:
Acne vulgaris.
Adult Dose
Topical/Cutaneous
Acne vulgaris
Adult: Apply to the affected areas once or twice daily (morning and evening). after the skin is gently washed and patted dry.
Child Dose
Renal Dose
Administration
Apply to the affected areas after the skin is gently washed and patted dry.
Contra Indications
History of regional enteritis or ulcerative colitis or history of antibiotic-associated colitis.
Precautions
Avoid contact w/ mouth, eyes, lips & mucous membranes; abraded or eczematous skin. May discolor hair & dyed fabrics. Pregnancy & lactation.
Lactation: Excretion in milk unknown/not recommended
Pregnancy-Lactation
Pregnancy Category: C
Lactation: Excretion in milk unknown/not recommended
Interactions
May enhance the action of neuromuscular blocking agents (e.g. atracurium). May antagonise the effects of parasympathomimetics. May competitively inhibit the effects of macrolides, ketolides, streptogramins, linezolid and chloramphenicol. Increased coagulation tests (prothrombin time/INR) and/or bleeding w/ vit K antagonists (e.g. warfarin, acenocoumarol, fluindione).
PABA sunscreens may transiently discolour fabric.
Side Effects
Side effects of Clindamycin + Benzoyl Peroxide :
Application site pain, Application site exfoliation, Application site irritation, Erythema, Burning, Pruritus, Sunburn, Scaling, Dryness, Diarrhea, Colitis, Peeling
Mode of Action
Clindamycin is a semi-synthetic derivative of lincomycin. It inhibits bacterial protein synthesis by reversibly binding to the 50S ribosomal subunits thus blocking the transpeptidation or translocation reactions of susceptible organisms.
Benzoyl peroxide has mild keratolytic effect and antimicrobial activity which is attributed to its potent oxidizing activity.
Clindamycin and Benzoyl peroxide are both active against Propionibacterium acnes, an organism associated with acne vulgaris.
Note
Benoxiclin 5gm + 1gm/100gm Gel generic name is Clindamycin + Benzoyl Peroxide. Benoxiclin 5gm + 1gm/100gm Gel is manufactured by Unimed & Unihealth Manufacturers Ltd.Benoxiclin is availble in all over Bangladesh.
Mes BD drug index information on Benoxiclin Gel is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.