Avil Injection
Pheniramine Maleate
45.5mg/2ml
Synovia Pharma PLC.
| Pack size | 2ml amp x 25's pack |
|---|---|
| Unite Price | 7.55 BDT |
Indications
Avil Injection is used for:
Allergic conditions, Motion sickness, Allergic conjunctivitis, Allergic rhinitis, Hypersensitivity reactions, Hay fever, Uritcaria with pruritus, Neurodermatitis
Adult Dose
Oral
Allergic conditions
Adult:
Syrup: 15-30 mg bid or tid.
Tablet: Up to 45 mg tid.
Max: 3 mg/kg/day.
Elderly: Syrup: 15-30 mg bid or tid. Tablet: Up to 45 mg tid. Max: 3 mg/kg/day.
Prophylaxis of motion sickness
Adult:
Syrup: 15-30 mg bid or tid.
Tablet: Up to 45 mg tid. Max: 3 mg/kg/day.
Take 1st dose at least 30 min before travelling.
Injection
The dosage should be adjusted individually.
When immediate or rapid response is desired, IV or IM injection should be used.
1-2 ml twice a day by I/M or slow IV
Multi-dose vial is not recommended for IV use.
Child Dose
Oral
Allergic conditions
Child:
Tablet
5-10 yr: Half a 45-mg tablet up to tid; Tablet: Up to 45 mg tid.
>10 yr: Syrup: 15-30 mg bid or tid.
Max: 3 mg/kg/day.
Prophylaxis of motion sickness
Child: As maleate: 5-10 yr: Half a 45-mg tablet up to tid; >10 yr: Syrup: 15-30 mg bid or tid. Tablet: Up to 45 mg tid. Max: 3 mg/kg/day. Take 1st dose at least 30 min before travelling.
Injection
Hypersensitivity reactions, Hay fever, Uritcaria with pruritus, Neurodermatitis
Injection solution is administered to infants and children aged 6 months and up to 11 years by the intramuscular route.
The recommended dose may be repeated at 12 hourly intervals until the acute symptoms have subsided.
Children aged 2 years about 11-14 Kg body weight
0.5-0.7 ml I/M.
Children aged 3-5 years 20 Kg body weight
0.8-1.3 ml I/M
Children aged 6-11 years Up to about 35 Kg body weight
1.0-1.5 ml I/M
Renal Dose
Administration
Should be taken with food. Take after meals.
Contra Indications
Symptomatic prostatic hypertrophy; neonates and premature infants.
Precautions
May impair ability to drive or operate machinery. Has potential for abuse. Narrow angle glaucoma, asthma or severe CV disease. Antiemetic effect may mask signs of other conditions. Pregnancy and lactation. Elderly.
Pregnancy-Lactation
Interactions
May mask ototoxicity produced by aminoglycoside antibiotics.
Potentially Fatal: Potentiation of CNS depression by alcohol, sedatives, opioids, barbiturates, hypnotics, narcoleptics. May increase antimuscarinic effect of MAOIs, atropine and TCAs.
Side Effects
Side effects of Pheniramine Maleate :
Sedation. Hypersensitivity reactions. Lassitude, dizziness, tinnitus, inability to concentrate, incoordination, irritability, insomnia and tremors. Nausea, vomiting, diarrhoea, colic, epigastric pain, anorexia, dryness of mouth and constipation. Urinary retention. Palpitations, headache. Blurred vision, increased intraocular pressure. Muscular weakness. Rarely, blood dyscrasias e.g. agranulocytosis, haemolytic anaemia.
Mode of Action
Pheniramine is an alkylamine derivative with histamine H1-receptor antagonist effects. It also has anticholinergic and moderate sedative effects.
Note
Avil 45.5mg/2ml Injection generic name is Pheniramine Maleate. Avil 45.5mg/2ml Injection is manufactured by Synovia Pharma PLC.Avil is availble in all over Bangladesh.
Mes BD drug index information on Avil Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.