Avaflut Nasal Spray
Fluticasone Furoate Nasal prep
27.5 mcg
Opso Saline Ltd.
| Pack size | 1's Pack |
|---|---|
| Unite Price | 250.00 BDT |
Indications
Avaflut Nasal Spray is used for:
Allergic rhinitis
Adult Dose
Nasal
Allergic rhinitis
Adult: As fluticasone furoate spray: 2 sprays (55 mcg) into each nostril once daily, may reduce to 1 spray (27.5 mcg) into each nostril once daily if symptoms are controlled.
Child Dose
Nasal
Allergic rhinitis (Seasonal/Perennial)
Child: 2-11 yr: 1 spray in each nostril once a day, may be increased to 2 sprays (55 mcg) into each nostril once daily if necessary.
Renal Dose
Administration
Contra Indications
Fluticasone Furoate nasal spray is contraindicated in patients with a hypersensitivity to any of its ingredients.
Precautions
Rarely, immediate hypersensitivity reactions or contact dermatitis may occur after the administration of Fluticasone Furoate nasal spray. Rare instances of wheezing, nasal septum perforation, cataracts, glaucoma and increased intraocular pressure have been reported following the intranasal application of corticosteroids, including Fluticasone Furoate. Although systemic effects have been minimal with recommended doses of Fluticasone Furoate nasal spray, potential risk increases with larger doses. Therefore, larger than recommended doses of Fluticasone Furoate nasal spray should be avoided.
Lactation: Unknown whether distributed in breast milk; caution advised
Pregnancy-Lactation
Pregnancy
Available data on inhaled or intranasal fluticasone propionate use in pregnant women have not reported a clear association with adverse developmental outcomes
Fluticasone propionate crossed the placenta following subcutaneous administration to mice and rats and oral administration to rabbits
Lactation
There are no available data on fluticasone propionate in human milk, effects on breastfed child, or effects on milk production
Developmental and health benefits of breastfeeding should be considered and adverse effects on breastfed child from treatment or from an underlying maternal condition
Interactions
May lead to increased plasma concentrations of fluticasone when used with CYP4503A4 inhibitors such as ritonavir.
Side Effects
Side effects of Fluticasone Furoate Nasal prep :
>10%
Headache (17%), URI (15%)
1-10%
Nasal congestion (8%), Pharyngitis (6-8%), Asthma symptoms (3-7%), Fever (1-5%), Dysphonia (4%), Cough (3-4%), Nasal discharge (1-3%), Aches and pains (1-3%), Flu-like syndrome (1-3%), Bronchitis (1-3%), Diarrhea (1-3%), Abdominal pain (1-3%), Nasal ulcer (1%)
Frequency Not Defined
Loss of taste
Potentially Fatal: Paradoxical bronchospasm.
Mode of Action
Fluticasone Furoate is a synthetic, trifluorinated corticosteroid that provides anti-inflammatory activity. It binds to glucocorticoid receptor and inhibits the migration of inflammatory mediator & cells (histamine, leukotrienes, mast cells, eosinophils etc)
Note
Avaflut 27.5 mcg Nasal Spray generic name is Fluticasone Furoate Nasal prep. Avaflut 27.5 mcg Nasal Spray is manufactured by Opso Saline Ltd.Avaflut is availble in all over Bangladesh.
Mes BD drug index information on Avaflut Nasal Spray is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.