Antepsin Tablet
Sucralfate
1gm
Kemiko Pharmaceuticals Ltd.
| Pack size | 100's pack |
|---|---|
| Unite Price | 5.52 BDT |
Indications
Antepsin Tablet is used for:
Peptic ulcer, Chronic gastritis, GI haemorrhage from stress ulceration
Adult Dose
Oral
Chronic gastritis; Peptic ulcer
Adult: 1 g 4 times daily or 2 g bid for 4-8 wk, may extend up to 12 wk if necessary. Maintenance dose of 1 g bid may be given to prevent the recurrence of duodenal ulcers. Max: 8 g daily.
Prophylaxis of gastrointestinal haemorrhage from stress ulceration
Adult: 1 g 6 times daily. Not to exceed 8 g daily.
Child Dose
Oral
Chronic gastritis; Peptic ulcer
Child: 1 mth-2 yr: 250 mg 4-6 times daily; 2-12 yr: 500 mg 4-6 times daily and 12-18 yr: 1 g 4-6 times daily.
Prophylaxis of gastrointestinal haemorrhage from stress ulceration
Child: 1 mth-2 yr: 250 mg 4-6 times daily;
2-12 yr: 500 mg 4-6 times daily and
12-18 yr: 1 g 4-6 times daily.
Renal Dose
Renal failure: Use with caution; aluminum salt may accumulate
Administration
Should be taken on an empty stomach. Take on an empty stomach 1 hr before or 2 hr after meals.
Contra Indications
Hypersensitivity.
Precautions
Systemic aluminum toxicity may occur in patients with chronic renal failure. Neonates, children; pregnancy and lactation.
Lactation: Probably safe because drug is minimally absorbed; unknown whether drug is excreted in breast milk
Pregnancy-Lactation
Pregnancy category: B
Lactation: Probably safe because drug is minimally absorbed; unknown whether drug is excreted in breast milk
Interactions
Avoid antacids within 30 min of sucralfate admin. May reduce absorption of tetracyclines, ranitidine, ketoconazole, theophylline, phenytoin, cimetidine and digoxin (ensure a dosing interval of at least 2 hr between admin of sucralfate and other non-antacid medications).
Side Effects
Side effects of Sucralfate :
1-10%
Constipation (2%)
<1%
Diarrhea, Dizziness, Dry mouth, Flatulence, Headache, Indigestion, Insomnia, Nausea, Vertigo, Vomiting
Frequency Not Defined
Bezoars formation, Gastrointestinal discomfort
Mode of Action
Sucralfate protects GI lining against peptic acid, pepsin and bile salts by binding with positively-charged proteins in exudates forming a viscous paste-like adhesive substance thus forming a protective coating.
Note
Antepsin 1gm Tablet generic name is Sucralfate. Antepsin 1gm Tablet is manufactured by Kemiko Pharmaceuticals Ltd.Antepsin is availble in all over Bangladesh.
Mes BD drug index information on Antepsin Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.