Indications
Adnix Tablet is used for:
Giardiasis, Cryptosporidiosis
Adult Dose
Oral
Giardiasis; Cryptosporidiosis
Adult: 500 mg every 12 hr for 3 days.
Child Dose
Oral
Giardiasis; Cryptosporidiosis
Child:
1-3 yr: 100 mg(5 ml) every 12 hr;
4-11 yr: 200 mg(10ml) every 12 hr;
>12 yr: 500 mg every 12 hr.
All doses to be taken for 3 days.
Renal Dose
Administration
Should be taken with food.
Contra Indications
Hypersensitivity.
Precautions
Renal and hepatic impairment. Pregnancy and lactation. Children <1 yr.
Pregnancy-Lactation
Interactions
May possibly interact with highly protein-bound drugs e.g. warfarin.
Side Effects
Side effects of Nitazoxanide :
1-10%
Headache (1%), Abdominal pain (8%), Diarrhea (2%), Nausea (3%), Chromaturia (2%), Vomiting (1%)
<1%
Increased ALT, Anorexia, Appetite increased, Creatinine increased, Diaphoresis, Dizziness, Eye discoloration (pale yellow), Fever, Flatulence, Infection, Malaise, Pruritus, Thinitis, Salivary glands enlarged, Urine discoloration
Mode of Action
Nitazoxanide is an antiprotozoal agent. Both nitazoxanide and its active metabolite (tizoxanide) interfere with the pyruvate:ferredoxin 2-oxidoreductase (PFOR) enzyme-dependent electron transfer reaction which is essential to anaerobic metabolism in susceptible organisms.
Note
Adnix 500 mg Tablet generic name is Nitazoxanide. Adnix 500 mg Tablet is manufactured by Alco Pharma LimitedAdnix is availble in all over Bangladesh.
Mes BD drug index information on Adnix Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.
Some other brands of Nitazoxanide :
Powder for Suspension
Alinix
100mg/5ml
Healthcare Pharmaceuticals Ltd.
Tablet
Alinix 500
500mg
Healthcare Pharmaceuticals Ltd.
Powder for Suspension
Atinid
100mg/5ml
Bio Pharma Laboratories Ltd.
Tablet
Atinid 500
500mg
Bio Pharma Laboratories Ltd.
Powder for Suspension
Dianide
100mg/5ml
General Pharmaceuticals Ltd.