Betson Ointment
Betamethasone dipropionate Topical
0.05%
Opsonin Pharma Limited
Pack size | 20 gm |
---|---|
Unite Price | 48.00 BDT |
Indications
Betson Ointment is used for:
Steroid-Responsive Dermatoses
Adult Dose
Topical/Cutaneous
Corticosteroid-responsive dermatoses
Adult: As betamethasone dipropionate cream, ointment, gel, lotion or solution: Apply thinly onto affected area 1-2 times daily for up to 2 weeks.
Child Dose
Renal Dose
Administration
Contra Indications
Topical: Untreated fungal, tubercular or bacterial skin infections; viral skin lesions (e.g. herpes simplex, varicella, vaccinia), acne vulgaris, rosacea, perianal and genital pruritus, perioral dermatitis, pruritus without inflammation;
Precautions
Chronic topical corticosteroid therapy may interfere with growth and development in children
Prolonged treatment with corticosteroids is associated with Kaposi sarcoma (consider discontinuation of therapy if diagnosed)
Discontinue if contact dermatitis occurs; not for use in patients with decreased skin circulation
Use may increase risk of posterior subcapsular cataracts and glaucoma; avoid contact with eyes;
Pregnancy-Lactation
Pregnancy
There are no available data on ointment use in pregnant women to identify a drug- associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes; observational studies suggest an increased risk of low birthweight infants with the use of greater than 300 grams of potent or very potent topical corticosteroid during a pregnancy; advise pregnant women that the ointment may increase risk of having a low birthweight infant and to use it on the smallest area of skin and for the shortest duration possible
Animal data
In animal reproduction studies, increased malformations, including umbilical hernias, cephalocele, and cleft palate, were observed after intramuscular administration to pregnant rabbits; the available data do not allow calculation of relevant comparisons between systemic exposure in animal studies to systemic exposure that would be expected in humans after topical use of the ointment
Lactation
There are no data regarding the presence of drug in human milk, effects on breastfed infant, or on milk production after topical ointment application to women who are breastfeeding
It is possible that topical administration of betamethasone dipropionate could result in sufficient systemic absorption to produce detectable quantities in human milk; the developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for therapy and any potential adverse effects on breastfed infant drug or from underlying maternal condition
To minimize potential exposure to breastfed infant via breast milk, use ointment on smallest area of skin and for shortest duration possible while breastfeeding; advise breastfeeding women not to apply ointment directly to nipple and areola to avoid direct infant exposure
Interactions
Side Effects
Side effects of Betamethasone dipropionate Topical :
Frequency Not Defined
Skin atrophy
Striae
Allergic dermatitis
Burning
Dry skin
Erythema folliculitis
Hypertrichosis
Irritation
Miliaria
Vesiculation
Acneform lesions
Pigmentation changes
HPA suppression (with higher potency used >2 wk)
Mode of Action
Corticosteroids decrease inflammation by stabilizing leukocyte lysosomal membranes, preventing release of destructive acid hydrolases from leukocytes, inhibiting macrophage accumulation in inflamed areas, reducing leukocyte adhesion to capillary endothelium, reducing capillary wall permeability and edema formation, decreasing complement components, antagonizing histamine activity and release of kinin from substrates, and reducing fibroblast proliferation, collagen deposition, and subsequent scar tissue formation
Note
Betson 0.05% Ointment generic name is Betamethasone dipropionate Topical. Betson 0.05% Ointment is manufactured by Opsonin Pharma LimitedBetson is availble in all over Bangladesh.
Mes BD drug index information on Betson Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.